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Main slide . Liquorice roots Names. Description. Constituents. Uses. Medications . Pharmacological effects. LICORICE. Main slide . Fruit form legume. Main slide . Main slide . Perennial small trees. Main slide .

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  1. Main slide • Liquorice roots • Names. • Description. • Constituents. • Uses. • Medications. • Pharmacological effects.

  2. LICORICE Main slide

  3. Fruit form legume Main slide

  4. Main slide

  5. Perennial small trees Main slide

  6. Roots outer surface brown or reddish brown while inner surface yellowish brown Main slide

  7. Roots outer surface brown or reddish brown while inner surface yellowish brown Main slide

  8. Licorice : Liquorice : Glycyrrhiza:Sweet roots : Radix Liquiritiae • Glycyrrhiza glabra- English, Spanish Licorice • Glycyrrhiza glandulifera – Russian Licorice • Glycyrrhiza violacea – Persian Licorice • Family : Leguminosae Main slide

  9. Perennial small trees . • Fruit form legume. • The roots outer surface brown or reddish brown while inner surface yellowish brown . • Odor : slight . • Taste : sweet . Main slide

  10. Chemical constituents • Glycoside –Saponin group : Glycyrrhizin 50 time sweeter than sugar . • Flavonoids –Liquiritin & Isoliquiritin • Proteins . • Sugars (glucose ,sucrose ). Main slide

  11. Main slide

  12. USES • Expectorant . • Antihistaminic . • Flavoring agent for Aloe , Quinine , NH4CL , Chocolates and others. • Anti-inflammatory activity –used in treatment of peptic ulcer ,seborrhea & mucous membranes ulcers . • Demulcent . • Soft drink . Main slide

  13. Candies Capsules Tablets Gum Tea Cigarettes Whole root Main slide

  14. Medications • Gingisan®: Liquid & ointment (oral) Chamomile flowers + Eucalyptus leaves + Licorice roots Treatment of gingivitis and stomatitis . • Midro tea Main slide

  15. N.B! • Glycyrrhizin increase fluids and sodium retention so decrease potassium ,so a person with cardiac problems and hypertension must avoid Licorice Main slide

  16. Through licorice lovers in the U.S.A rarely eat enough glycyrrhizic acid to get a blood-pressure boost. • European physicians are now debating whether moderate doses of natural licorice have a significant hypertensive effect. • Glycyrrhizic acid, which makes up from 4 to over 20% of the root, is not the only biologically active molecule. • About 300 different polyphenols, which make up 1 to 5% of the root, are suspected antioxidants, perhaps even cancer-fighting compounds. Main slide

  17. Licorice helps heal ulcers by inactivating 15-hydroxyprostaglandin dehydrogenase in the stomach lining. As with cortisol in the kidney, licorice locally extends the life of prostaglandins that protect the stomach wall. • The effect on prostaglandins may also explain why licorice helps soothe a cough. The extract added to some cough drops may affect the prostaglandins that release mucous. Main slide

  18. But getting in the cogs of bio-regulation pathways isn't always beneficial. • Because glycyrrhizic acid allows cortisol to stick around in the distal tubules of the kidney, cortisol binds to a protein that causes the kidney to retain sodium longer than it normally would, increasing blood pressure. • Other effects of high licorice consumption include water retention, headaches, lethargy, and, in massive amounts, heart failure. Main slide

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