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Treatment Options for Post-MI patients with LVD – are all ACE Inhibitors Equal?

This program provides an overview of treatment options for post-myocardial infarction (MI) patients with left ventricular dysfunction (LVD). It explores the influence of LV dysfunction on post-MI outcomes, the predictive value of markers of organ damage, and the targeting of neurohormonal pathways. The ESC guideline recommendations and distinguishing between agents in the same class are discussed. The program also covers the cardioprotective effects of Zofenopril and the effects of ACE inhibitors on endothelial stress. SMILE-4, a subanalysis focusing on ACE inhibitors in combination with aspirin, and SMILE-ISCHEMIA, analyzing patients with preserved LV function, are included. Conclusions and abbreviations are provided.

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Treatment Options for Post-MI patients with LVD – are all ACE Inhibitors Equal?

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  1. Treatment Options for Post-MI patients with LVD – are all ACE Inhibitors Equal?

  2. Program Overview

  3. Influence of LV Dysfunction on Post-MI Outcomes

  4. Predictive Value of Markers of Organ Damage

  5. Treatment Options: Targeting Neurohormonal Pathways

  6. ESC Guideline Recommendations

  7. Distinguishing Between Agents in the Same Class: Considerations

  8. Class Effect: ACE Inhibitors Post-MI

  9. SMILE: Overview

  10. SMILE: Rationale

  11. Cardioprotective Effects of Zofenopril

  12. Effects of ACE Inhibitors on Endothelial Stress

  13. SMILE-4: Distinguishing Between ACE Inhibitors in Combination With Aspirin

  14. SMILE-4: Subanalysis in Hypertensive Patients

  15. SMILE-ISCHEMIA: Analysis of Patients With Preserved LV Function

  16. Conclusions

  17. Abbreviations

  18. Abbreviations

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