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Fungi

Fungi. “a group of diverse and widespread unicellular and multicellular organisms, lacking chlorophyll, usually bearing spores and often filamentous”. Fungal Infections. 10 years nosocomial organic compounds and carbon: energy aerobic or facultatively anaerobic. Categories of Fungi.

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Fungi

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  1. Fungi “a group of diverse and widespread unicellular and multicellular organisms, lacking chlorophyll, usually bearing spores and often filamentous”

  2. Fungal Infections • 10 years • nosocomial • organic compounds and carbon: energy • aerobic or facultatively anaerobic

  3. Categories of Fungi • 1) yeasts • 2) molds • 3) dimorphic fungi

  4. Yeasts • spherical or oval • “budding” • 1 yeast cell can produce up to 24 daughter cells by “budding” • short chain of cells

  5. Molds • thallus (body) • hyphae • septa • septate hyphae

  6. Dimorphic Fungi • 2 forms of growth in pathogenic species • 1) mold • 2) yeast • Mold: hyphae (multicellular) • Yeast: buds (unicellular)

  7. Dermatomycosis • dermatophytes • epidermis, hair, and nails • enzyme: keratinase • direct contact, infected hairs and epidermal cells • 3 genera

  8. Coccidioidomycosis • Readings question #1: What is coccidioidomycoses? What microorganism causes this disease and where is it found? How is it transmitted? • San Joaquin Fever

  9. Diagnosis • Spherules (spores) in tissues or fluids • Tissues, lesions • Laboratory workers: infectious aerosols • Increasing in California and Arizona

  10. Histoplasmosis • Readings question #2: What is the causative microorganism? Where is this microorganism found? How is the disease acquired?

  11. Candidiasis • Bacterial microbiota (genitourinary tract) • Antibacterial drugs • Normal mucosal pH • Readings question #3: What microorganisms cause candidiasis? How may this infection appear in infants? What is it called?

  12. Cryptococcosis • Spherical cells, budding • Polysaccharide capsules • Soil, pigeon roosts and nests • Inhalation of dried droppings

  13. Brain Tissue with Cavities

  14. Aspergillosis • Readings question #4: What is the causative fungus? Where is it found? How is it spread? What are the symptoms for the disease?

  15. Pneumocystis Pneumonia(PCP) • Healthy human lungs • High infection rate in general population • Lining of the alveoli • Diagnosis: sputum samples

  16. Readings Question #5 • How is the disease PCP spread? What are its symptoms? Is it potentially fatal? (If yes, how does death occur?)

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