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אסימטריה צרברלית מבט קליני PowerPoint PPT Presentation


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אסימטריה צרברלית מבט קליני. המיספרה שמאל. המיספרה ימין. סיכום השיעור הקודם. קשיים בהגדרת תפקוד מנטאלי קשיים בקביעת גבולות בין אזורי מוח שונים. אסוציאציות, דיסוציאציות ודיסוציאציות כפולות. מיפוי ציטוארכיטקטוני מפת Broadman מיפוי תפקודי: אזורים סנסוריים ראשוניים אזורים מוטוריים ראשוניים

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אסימטריה צרברלית מבט קליני

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  • .

  • , .

  • Broadman

  • :

  • .


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  • (Split Brain).

  • : .


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  • (Split Brain).

  • : .


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  • , , .

  • , :

  • "" ?

    Cerebral commissures


Corpus callosum

(corpus callosum)

  • -200 800 . ( ~ 12). .

  • ,

Genu

Body

Splenium

Rostrum


Anterior and posterior commissures

Anterior and posterior commissures

  • -CC

  • -AC (temporal lobes).

  • -PC , ' .

Anterior Commissure

Posterior Commissure


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  • -CC ((homotypic; (heterotopic)

  • -CC , (neural oscillations). -CC .

  • -CC (inhibitory) "" .


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CC

  • - , .

  • -CC.

  • (level of activation) -CC:

  • (DTI) Diffusion Tensor Imaging

  • (FA) Fractional Anisotropy

  • -FA

Putnam et al., JoN, 2008


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Front

:R > L

: L > R

I.

Lateral sulcus:

II.

Right Hemisphere

Left Hemisphere

Supra-temporal plane:

1.

2.

III.

IV.

Back


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  • (Split Brain).

  • : .


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  • :

    • Marc Dax (Montpellier, 1936(

    • " Broca Leborgne (1861(

    • Carl Wernicke

  • (Major and minor hemispheres) Hughlings Jackson (1864).

    • .

  • Functional Lateralization

    • -

    • //

    • //


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  • (Split Brain).

  • : .


Disconnection syndromes

"" Split Brain))

- Commissurotomy:

-

-cross cuing

:

-RH

(mild akinesia)

:

Volitional ambivalence

Callosal Alexithymia

Intermanual conflict

Anarchic (alien) hand

Left hand ideomotor apraxia

Disconnection syndromes

Roger Sperry

Mike Gazzaniga


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CC


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( ).

" ".

.


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  • :


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A

A

B

B

  • ( ) KID.

  • . , CAT.

  • . ( -PI -PENCIL 4 ).

  • , .

:


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-

  • Split Brain :

  • ( , , , )

  • : .

  • , ( ) .


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  • :

  • -


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-


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- -

Block Design


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  • :

  • -


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-


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-

?


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  • :

  • -


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,

:


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-


Split brain

Split Brain

  • ( ) , cross-cuing.

  • ( ) .

  • ( , ).

  • , .

  • , domain specificity

  • ? ?


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  • (Split Brain).

  • : .


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Critical region: TPJTemporo-parietal Junction

,


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WADA

""((sodium amobarbital ( -internal carotid artery -femoral artery).

Frequency histogram of the bimodal distribution of hemispheric language lateralization indices (x-axis) in 188 healthy right-handed subjects as assessed by fTCD

Knecht, S. et al. Brain 2000 123:74-81;


Hemispheric asymmetry for kana and kanji

Hemispheric asymmetry for Kana and Kanji

Kana

Kanji

daigaku (university)(lit.: "big learning")with furigana (above)

Kanji Kana.


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  • ;Infantile hemiplegiaHemispherectomy .

    • .

    • -IQ ( , ).

    • : . ( .)


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-IH


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  • ;Infantile hemiplegiaHemispherectomy .

    • .

    • -IQ ( , ).

    • : . ( .)

    • .

  • .


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- - 2

  • ( , '), .

  • .

  • :


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.

.

:

, , .

?


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.

.

(lateralized) , ( -).


Funnel et al

Funnel et al.

  • -Split Brain Syndrome

  • -Corpus Callosum .

  • -.

  • .

  • .

  • -split brain

  • -split brain


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?


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