Seminar Assignment. HT 2011. Seminar assignment. Handed out at course start Group work / individual assessment Research based aspects, requires independent work Obtain appropriate information - lectures, discussions, web, articles ..… Time scheduled to prepare answer
Seminar assignment - Why?
Common genetic variants associated
with plasma lipoprotein levels
The fine-mapping analysis identifies a SNP in the promoter of gene X.
You suspect that the SNP might have an impact on the rate of transcription of gene X.
You therefore decide to investigate the mRNA expression of gene X in a set of liver biopsies from 100 Sami subjects.
You discover that there is a strong relationship between hepatic gene X mRNA levels and circulating cholesterol concentrations.
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