1 / 136

Toxins

Toxins. Slackers Facts by Mike Ori. Disclaimer. The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes.

dani
Download Presentation

Toxins

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Toxins Slackers Facts by Mike Ori

  2. Disclaimer The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes. The document can mostly be used forward and backward. I tried to mark questionable stuff with (?). If you want it to look pretty, steal some crayons and go to town. Finally… If you’re a gunner, buck up and do your own work.

  3. List the staph aureus toxins

  4. Alpha toxin Exfolatin Pyrogenic Toxin Superantigens (PTSAgs) Enterotoxin Toxic Shock Syndrome Toxin (TSST)

  5. Alpha toxin effects

  6. Pore forming exotoxin

  7. Exfolatin symptoms

  8. Exfoliation at epidermal stratum spinosum and stratum granulosum

  9. PTSags action

  10. Activates T cells via MHC-II interaction with APC regardless of TCR fit

  11. Staph food poisoning toxin

  12. Staph Enterotoxins (PTSags)

  13. Enterotoxin effect

  14. Vomiting by direct action on nerves.

  15. TSST effects

  16. Superantigen based shock

  17. M protein producer

  18. Group A strep (pyogenes)

  19. M protein effect

  20. Surface antigen Fixes serum factor H which inactivates complement

  21. Group A Strep (GAS) toxins

  22. Streptolysin O Streptococcal PryogenicExotoxin (Spe)

  23. Streptolysin O function

  24. Pore forming exotoxin

  25. Streptolysin O serum sign

  26. Anti Strep O antibodies (ASO)

  27. Toxin similar to Strep Pyrogenic Exotoxin (Spe)

  28. PTSAgs

  29. Spe effects

  30. Systemic effects like fever, rash

  31. Strep agalactiae surface antigen

  32. Polysaccharide capsule

  33. Strep pneumoniae pore forming exotoxin

  34. Pneumolysin

  35. Pneumolysin function

  36. Pore forming exotoxin

  37. Pneumolysin target cells

  38. Respiratory epithelium

  39. Strep pneumoniae antigen

  40. Polysaccharide capsule

  41. Corynebacteriumdiphtheriae toxin

  42. Diphtheria toxin (DT)

  43. DT function

  44. A-B toxin that ADP-ribosylates ribosome EF-2 to halt protein synthesis.

  45. Internalin producer

  46. Listeria

  47. Interalin function

  48. Facilitates Listeria entry into cell

  49. Listerlysin O function

  50. Pore forming exotoxin

More Related