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Infectious Diseases Unit 4 Lesson 5 plan - PowerPoint PPT Presentation


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Infectious Diseases Unit 4 Lesson 5 plan. Do now. Brainstorm: The 1918 flu appeared suddenly and killed millions of people. Where does a virus like this come from? . Antigenic drift and Antigenic shift . Antigenic drift and Antigenic shift . Only some viruses can do this because

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Do now

  • Brainstorm:

    • The 1918 flu appeared suddenly and killed millions of people. Where does a virus like this come from?


Antigenic drift and Antigenic shift


Antigenic drift and Antigenic shift

Only some viruses can do this because

It requires a segmented genome!


Non-Segmented Genomes

Virus B

Virus A

Host cell


Segmented Genomes

Virus B

Virus A

Host cell


H = hemagglutinin (surface protein used to attach and enter host cell)

N = neuraminidase (surface protein used to exit host cell)

Examples:

H1N1: infects cells of upper respiratory tract; less virulent but easily spread

H5N1: infects cells of lower respiratory tract; more virulent but not easily spread




Wrap up

  • Complete your worksheet and hand it in.


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