Infectious Diseases Unit 4 Lesson 5 plan. Do now. Brainstorm: The 1918 flu appeared suddenly and killed millions of people. Where does a virus like this come from? . Antigenic drift and Antigenic shift . Antigenic drift and Antigenic shift . Only some viruses can do this because
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Only some viruses can do this because
It requires a segmented genome!
N = neuraminidase (surface protein used to exit host cell)
H1N1: infects cells of upper respiratory tract; less virulent but easily spread
H5N1: infects cells of lower respiratory tract; more virulent but not easily spread