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Table 1: Average hexon positive numbers per view. Titers: Beta-Gal: 1.0x10 9 pfu/ml; LacZ: 1.72x10 9 pfu/ml Del C drf: 1.99 x10 9 pfu/ml; Del C sha: 4.09 x10 9 pfu/ml. Fig1. Insulin Secretion after glucose and/ or secretagogues’ stimulation in 832/13 cells.

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Table 1: Average hexon positive numbers per view

Titers:

Beta-Gal: 1.0x109 pfu/ml;

LacZ: 1.72x109 pfu/ml

Del C drf: 1.99 x109 pfu/ml;

Del C sha: 4.09 x109 pfu/ml


Fig1. Insulin Secretion after glucose and/ or secretagogues’ stimulation in 832/13 cells

Forskolin, an agent that elevates cellular

Camp via stimulation of adenylate cyclase.

Tolbutamide, interacts with the sulfonylures

receptor to cause channel closure,

and diazoxide, an opener of the channel

Insulin content of 832/13 cells

after adenovirus treatment


Real time PCR data from 5 LacZ and 5 Delta C, 3 experiments secretagogues’ stimulation in 832/13 cells

48hrs, adenovirus dilution 1:100


Real time PCR data from 6 LacZ and 6 Delta C, once experiment

P-Value: insulin, 0.01907; Pdx-1 is 0.000493

48hrs, adenovirus dilution 1:200


Del C1 experiment

Del C2

Del C3

Del C3

LacZ3

Del C2

LacZ2

Del C1

LacZ1

LacZ2

LacZ3

LacZ1

Anti-cMyc

Anti-eif2alpha

Anti-eif2alpha p


Del C1 experiment

Del C2

Del C3

Del C3

LacZ3

Del C2

LacZ2

Del C1

LacZ1

LacZ2

LacZ3

LacZ1

Anti-gck

Anti-pdx-1


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