Infective Endocarditis (IE). A microbial infection of a cardiac valve or the endocardium caused by bacteria, fungi, or chlamydia Often categorized as acute or subacute based on the rapidity of the clinical course
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Karchmer, Scientific American Medicine, 1999
*Endothelial damage caused by turbulent blood flow seen in congenital or acquired heart disease
A – C. Osler Nodes: D. Janeway lesion