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MDI insulin + placebo

EMPA-REG MDI trial: Effect of empagliflozin on daily insulin dose needed to achieve glycaemic control. MDI insulin + placebo. MDI insulin + empagliflozin 10 mg. MDI insulin + empagliflozin 25 mg. Insulin dose (IU/day). Week 1-18: stable total daily insuline dose.

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MDI insulin + placebo

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  1. EMPA-REG MDI trial: Effect of empagliflozin on daily insulin dose needed to achieve glycaemic control MDI insulin + placebo MDI insulin + empagliflozin 10 mg MDI insulin + empagliflozin 25 mg Insulin dose (IU/day) Week 1-18:stable total daily insuline dose Week 19-40:treat-to-target period, Insulin dose adjusted Week 41-52:Insuline dosedas in week 40 week Rosenstock et al., Diab Care 2014

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