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Chapter 3 Tissue Development, Repair, & Unusual Growth

Chapter 3 Tissue Development, Repair, & Unusual Growth. Germ Layers & Specialization. Mesoderm. Ectoderm. Endoderm. Specialization. Developmental Aspects of Tissue. Epithelial tissue -germ layers: endoderm, mesoderm, ectoderm Muscle and Connective tissue - mesoderm Nervous tissue

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Chapter 3 Tissue Development, Repair, & Unusual Growth

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  1. Chapter 3Tissue Development, Repair, & Unusual Growth

  2. Germ Layers & Specialization Mesoderm Ectoderm Endoderm

  3. Specialization

  4. Developmental Aspects of Tissue • Epithelial tissue -germ layers: endoderm, mesoderm, ectoderm • Muscle and Connective tissue -mesoderm • Nervous tissue -ectoderm • Old age = decrease in mass & viabililty

  5. Tissue Repair 1. Regeneration • Replacement by the same kind of cells 2. Fibrosis • Repair by dense fibrous connective tissue (scar tissue) 3. Determination of method • Type of tissue damaged • Severity of the injury

  6. Events in Tissue Repair 1.Capillaries become very permeable • Clotting proteins leak through • Clot walls off injured area 2. Formation of granulation tissue • Many capillaries and WBCs 3. Regeneration of surface epithelium • Develops beneath scab • Over the scar

  7. Regeneration of Tissues • Tissues that regenerate easily - Epithelial tissue - Fibrous connective tissue and bone • Tissues that regenerate poorly - Skeletal muscle • Tissues that are replaced largely with scar tissue (amitotic at maturity) - Cardiac muscle - Nervous tissue within the brain and spinal cord

  8. 1.Neoplasm – mitosis gone crazy; tumor Benign – doesn’t spread; stays local Malignant – cancerous; invades; spreads via blood – called metastisis Carcinogens – agents that cause cancer; build up of mutations Changes in Growth Patterns

  9. 2. Hyperplasia – temporary enlargement of localized tissues; i.e. breasts during pregnancy; can be normal or abnormal

  10. 3. Atrophy – decrease in size due to lack of use

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