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Thailand Researches in Microbiological Risk Assessment : Past & Present

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Thailand Researches in Microbiological Risk Assessment : Past & Present. Suphachai Nuanualsuwan DVM, MPVM, PhD. Risk Analysis (Codex). Risk communication. Risk assessment. Risk management. Suphachai DVM, MPVM, PhD. Risk Assessment (RA).

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Presentation Transcript
slide1

Thailand Researches in

Microbiological Risk Assessment

: Past & Present

Suphachai Nuanualsuwan

DVM, MPVM, PhD

slide2

Risk Analysis (Codex)

Risk

communication

Risk

assessment

Risk

management

Suphachai

DVM, MPVM, PhD

slide3

Risk Assessment (RA)

1. A process of systematic and objective evaluation of all available information pertaining to foodborne hazards.

2. This process identifies (& quantifies) the risk.

Suphachai

DVM, MPVM, PhD

slide4

Risk Management (RM)

1. The process of weighing policy alternatives in the light of the result of risk assessment, if required, and selecting and implementing appropriate control option, including regulatory measures.

2. This process controls or prevents the risk

Suphachai

DVM, MPVM, PhD

slide5

Risk Communication (RC)

1. The interactive exchange of information and opinions concerning risks and risk management among risk assessors, risk managers, consumers, and other interested parties.

2. This process informs others of the risk.

Suphachai

DVM, MPVM, PhD

slide6

Risk Analysis (CAC)

Risk

communication

Risk

assessment

Risk

management

Suphachai

DVM, MPVM, PhD

slide7

Risk Assessment

  • Hazard Identification (HI)
  • Hazard Characterization (HC)
  • Exposure Assessment (EA)
  • Risk Characterization (RC)

Suphachai

DVM, MPVM, PhD

slide8

ประเมินความเสี่ยง

  • การระบุอันตราย
  • การอธิบายอันตราย
  • การประเมินการสัมผัส
  • การอธิบายความเสี่ยง

Suphachai

DVM, MPVM, PhD

slide9

Risk Assessment

1. Hazard Identification

2.Hazard Characterization 3.Exposure Assessment

4. Risk Characterization

Suphachai

DVM, MPVM, PhD

slide10

Risk Assessment

1.Hazard Identification

The identification of biological, chemical, and physical agents capable of causing adverse health effects and which may be present in a particular food or group of foods.

Suphachai

DVM, MPVM, PhD

slide11

Risk Assessment

3. Exposure Assessment

The qualitative and/or quantitative evaluation of the likely intake of biological, chemical, and physical agents via food as well as exposures from other sources if relevant.

Suphachai

DVM, MPVM, PhD

slide12

Risk Assessment

3. Exposure Assessment

  • Probability of exposure
  • Prevalence (%)
  • Concentration (CFU/g or MPN/ml)
  • Consumption (g/day)
  • Dose (CFU or MPN)

Suphachai

DVM, MPVM, PhD

slide13

Risk Assessment

3. Exposure Assessment

Probability density

Suphachai

DVM, MPVM, PhD

Probability of Exposure

slide14

Risk Assessment

2. Hazard Characterization

The qualitative and/or quantitative evaluation of the nature of the adverse health effects associated with the hazard. For the purpose of Microbiological Risk Assessment the concerns relate to microorganisms and/or their toxins.

Suphachai

DVM, MPVM, PhD

slide15

Risk Assessment

2. Hazard Characterization

“ Dose-response assessment ” previously

Response

Suphachai

DVM, MPVM, PhD

Dose

slide16

Risk Assessment

4. Risk Characterization

The process of determining the qualitative and/or quantitative estimation, including attendant uncertainties, of the probability of occurrence and severity of known or potential adverse health effects in a given population based on hazard identification, hazard characterization and exposure assessment.

Suphachai

DVM, MPVM, PhD

slide17

Risk Assessment

4. Risk Characterization

Probability density

Suphachai

DVM, MPVM, PhD

Risk

slide18

MRA Projects : Past & Present

Year Host Risk Hazard Commodity PI

2545 ACFS EA VP Shrimp A.Orasa

2546 ACFS MRA Salmonella Chicken A.Sumontha

MRA C. jejuni Chicken A.Pravate

MRA VP Crab meat A.Pensri

2548 ACFS EA N/A Consumption A.Wongswat

Suphachai

DVM, MPVM, PhD

VP : V. parahaemolyticus PI : Principal investigator

slide19

MRA Projects : Past & Present

Year Host Risk Hazard Commodity PI

2549 ACFS MRA L.monocytogenes Chicken Dr.Suphachai

BIOTEC MRA Staph. aureus Nham Muu Dr.Ruud

2551 BIOTEC MRA VP Shrimp Dr.Wrapa

BIOTEC MRA Salmonella Vegetable Dr.Wrapa

2552 BIOTEC HC Salmonella + VP N/A Dr.Suphachai

Suphachai

DVM, MPVM, PhD

VP : V. parahaemolyticus PI : Principal investigator

slide20

Research Categorization

Risk analysis

Commodity

&

Market

Hazard

Application

Suphachai

DVM, MPVM, PhD

slide21

Risk management via Models

Research Categorization

Food safety objective (FSO) concept

Appropriate level of protection (ALOP)

Cases / year

Process criteria

Performance criteria

Pasteurization

Consumption

Raw material

Illness

Food

Storage/Distribution

PO

PO

Performance objective

Microbiological criteria

Food safety objective

(FSO)

MRA

RISK ANALYSIS

Suphachai

DVM, MPVM, PhD

slide22

Research Categorization

  • HAZARD
    • Bacteria
      • Infection : Salm., VP., Campy., Cronobacter
      • Intoxication : Staph.aureus, B.cereus, Clostridium
    • Viruses
      • Norovirus (Norwalk, previously)
      • Hepatitis A virus
      • Hepatitis E virus
    • Protozoa & Parasite

Suphachai

DVM, MPVM, PhD

slide23

Research Categorization

APPLICATION

  • Risk estimate
  • Setting Microbiological limit (ML)
  • Setting Microbiological criteria (MC)
  • Consumer protection (Thais)
    • Domestic
    • Import (in conjunction with Thai FDA)
slide24

Research Categorization

COMMODITY & MARKET

  • Geography : Land, Sea
  • Species : Animal, Plant
  • Cook vs. Raw (RTE vs. export)
  • Domestic vs. International markets
  • Domestic : Locally made vs. Import
  • International : Low end vs. Hi end (countries)

Suphachai

DVM, MPVM, PhD

slide25

Research Gap

Commodity

Shrimp Chicken Pork Vegetable etc.

Hazard

Salm. VP. Campy. Virus

Suphachai

DVM, MPVM, PhD

slide26

Research Gap

  • MRA is only a snap shot info. (not realtime)
  • Qualitative vs. Quantitative MRA
  • Prioritized by
    • Thai population
      • risk estimate
      • setting FSO
      • setting MC
    • Export or driven by food industries

Suphachai

DVM, MPVM, PhD

slide27

Researcher Gap (Institutional perspective)

  • Researchers
    • Academia & Institutes (now)
    • Graduate students (next)
  • Trainings
  • Collaboration & Communication
  • Networking
  • Information & Methodology
  • Commitment
  • Funding

Suphachai

DVM, MPVM, PhD

slide28

Suphachai

DVM, MPVM, PhD

slide29

Welcome

Comments & Discussion

Thank you

for your attention

Suphachai

DVM, MPVM, PhD

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