Mobile phone use and acoustic neuroma risk in Korea.
Jae-wook Choi1)Songyi Yoon1) Dong-Soo Yoo2)Hae-Joon Kim1) Joon-young Lee3) Soo-Ho Shim1) Mun-seob Ahn1) Kyong-Hee Kim) Jeung-Hun Kim4) Chul-Ki Park5) Sung-Suk Lee6) Hae-Rim Park7) Yong-Ku Jeong8) Yong-Sik Kim9) Kyung-Mi Park10)
Department of Preventive Medicine, College of Medicine, Korea University1) Graduate School Korea University2) Department of Biostatistics, Korea university3) Seoul Asan Hospital4) Seoul National Hospital5) Korea Canter Center Hosptial6) Hanrim Unversity Hospital7) Korea University Anam Hospital8) Korea University Ansan Hospital9)Sanggye Paik Hospital10)
*Corresponding author: Jae-wook Choi([email protected])
Cancer incidence by region, Age-standardized incidence rate (ASR) Unit: cases, per 100,000 Male (Left), Female (Right)
Male (Left) Female (Right)Brain Tumor (Blue) Acoustic Neuroma (Red)
Establishment of target disease reporting system
Pathology, Neurosurgery and ENT department of
Nine University hospital in Seoul and Kyungi province
Validity verification of Exposure Assessment model
Case-Control selection (Sex-age-matching)
A part of mobile phone user
Exposure Assessment model
(Analog/Digital, Total call time,
Average daily minutes of use)
Total call time
Case-control research accomplishment
Derivation Development Odds Ratio
Figure 1. Case-control study design
†χ²-test. §studentt-test: * p<0.05, **p<0.001.
†The odds ratio (OR) and 95% confidence interval (CI) were calculated by unconditional multiple logistic regression analysis with fifteen categorize variables [ gender(1:male, 0:female); age(1:>20years, 2:20-29years, 3:30-39years, 4:40-49years, 5:50-59years, 6:≤60) years; residential district(1:rural area, 0:urban area);smoking habits(1:yes, 0:no); drinking habits(1:yes, 0:no);sleeping hours(1:<7hours, 0:≥7hours);hair dyeing(1:yes, 0: no);cancer in family members in a direct line(1:yes, 0:no); stress(1:yes, 0:no); Mobile phone use(1:yes, 0:no); Cumulative length of use(1:Non use, 2: <48months, 3:48-83months, 4:≥84months); Cumulative call time(1:Non use, 2:<300hours, 3: 300—899hours, 4:≥900hours); monthly fee (1:Non use, 2:<30,000won, 3:30,000-49,999won, 4:50,000-79,999won, 5:≥80,000won); Regular side of mobile phone use(1:right, 2:left, 3:both, 4:don’t know); Laterality(1:Non use, 2:Ipsi-use, 3:Contra-use, 4:both).