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SMAD 4/ DPC4 and Colon Cancer

SMAD 4/ DPC4 and Colon Cancer. Morphological and molecular analyses of Smad4-/- embryos (Right) and their littermate controls (Left). . Yang X et al. PNAS 1998;95:3667-3672. References. Beretta G, Braud F, Kildani B, et. al. (2010) Colon Cancer. Oncology/Hematology 74(2), 106- 133

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SMAD 4/ DPC4 and Colon Cancer

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  1. SMAD 4/ DPC4and Colon Cancer

  2. Morphological and molecular analyses of Smad4-/- embryos (Right) and their littermate controls (Left). Yang X et al. PNAS 1998;95:3667-3672

  3. References • Beretta G, Braud F, Kildani B, et. al. (2010) Colon Cancer. Oncology/Hematology 74(2), 106- 133 • Deng C, Li C, Xu X, Yanh X. (1998) The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice. PNAS. 95(7) 3667-3672 • Fleming N, Jorissen R, Mouradov D, et. al. (2012) SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer. The Journal of Cancer Research 73. 725-735 • Li X, Liu B, Ma J, Xiao J, Zhang Y. (2011) Roles of VEGF-C and SMAD4 in the Lymphangiogenesis, Lymphatic Metastasis, and Prognosis in Colon Cancer. Journal of Gastrointestinal Surgery 15(11), 2001-2010 • Malkoski S, Wang X. (2012) Two sides of the story? SMAD4 loss in pancreatic cancer versus head and neck cancer. FEBSLetters. 586 • Xiao D, Wen J, Li J, et. al. (2006) Effect of DPC4 Gene Invasion and Metastasis of Colorectal Carcinoma Cells. ABBS. 38(12) 883-892

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