Cardiovascular disease risk assessment
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CARDIOVASCULAR DISEASE RISK ASSESSMENT. Cardiovascular disease (CVD) Definition. Cardio- = The Heart -Vascular= Blood Vessels Cardiovascular diseases = disease of The Heart + Blood vessels. Atherosclerosis. Blood vessels disease can occur everywhere!. STROKE. Coronary Heart Disease.

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CARDIOVASCULAR DISEASE RISK ASSESSMENT

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CARDIOVASCULAR DISEASE RISK ASSESSMENT


Cardiovascular disease (CVD) Definition

  • Cardio- = The Heart

  • -Vascular= Blood Vessels

  • Cardiovascular diseases = disease of The Heart + Blood vessels


Atherosclerosis


Blood vessels disease can occur everywhere!


STROKE


Coronary Heart Disease


Aortic Aneurysm


Peripheral Artery Disease


Cardiovascular Diseases

Stroke

Coronary Heart Disease

Aortic Aneurysm

Peripheral Artery Disease


What is your LIFETIME risk?


Life time risk of Coronary Heart Disease

  • At 40 years old

    • 1 in 2 man

    • 1 in 3 woman

Lifetime risk of developing coronary heart disease.

Lloyd-Jones DM, Larson MG, Beiser A, Levy D

Lancet. 1999;353(9147):89


Already in very high risk

  • Established cardiovascular disease

  • Diabetes

  • Chronic kidney disease


Cardiovascular disease & Diabetes

Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age

Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791


Major risk factors

  • Increasing age

  • High cholesterol

  • High blood pressure

  • Smoking


Lifetime risk of Cardiovascular disease

Risk factors

  • Cholesterol

  • BP

  • Smoking

70%

50%

5%

8%

Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age

Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791


Median survival

Risk factors (RF):

  • BP≥160/100

  • Total Cholesterol ≥ 6.2

  • Smoking

Year


How high is your 10-YEAR risk?


Cardiovascular disease – 10yr risk

  • The Framingham predictor

  • http://hp2010.nhlbihin.net/atpiii/calculator.asp?usertype=prof


Calculate the points according to your – Total cholesterol level


Calculate the points according to your - Age


Smoke or not?


“Good cholesterol” (HDL) level ??


Blood pressure??


Get the Sum! -> and your risk


High Cholesterol – treat or not?


Major risk factors

  • Age (M≥45, F≥55)

  • Family history of heart attack or sudden death before 55years (M) or 65years (F)

  • Current cigarette smoking

  • High blood pressure 140/90mmHg or on treatment

  • HDL<1.03mmol/L

  • HDL>1.55mmol/L -> remove one risk factor


High cholesterol – treat or not?


Thank you ; )

Wish you all a health heart


Cardiovascular disease & Blood pressure

>160

140-159

130-139

<120

Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age

Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791


Cardiovascular disease & Total Cholesterol

6.19

5.16-6.18

4.64-5.15

<4.16

Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age

Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791


Major risk factors

  • Increasing age

  • High cholesterol

    • High “bad cholesterol” (LDL)

    • Low “good cholesterol” (HDL)

  • High blood pressure

  • Smoking

  • Family history of heart attack or sudden death


Borderline risk factors

  • Systolic pressure 120 to 139 mmHg

  • Diastolic pressure 80 to 89 mmHg

  • LDL-cholesterol 2.6 to 4.1 mmol/L

  • HDL-cholesterol 1.0 to 1.5 mmol/L

  • Impaired fasting glucose without overt diabetes

  • A past history of smoking


  • Total Chlos >=6.2

  • SBP>=160

  • DBP>=100

  • Smoking

  • Diabetes

  • Non-optimal

  • Total chol 4.65-5.15

  • SBP120-139

  • DBP80-90


Borderline risk factors

  • Systolic pressure 120 to 139 mmHg

  • Diastolic pressure 80 to 89 mmHg

  • LDL-cholesterol 100 to 159 mg/dL (2.6 to 4.1 mmol/L)

  • HDL-cholesterol 40 to 59 mg/dL (1.0 to 1.5 mmol/L)

  • Impaired fasting glucose without overt diabetes

  • A past history of smoking


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