Biological chemistry. Carl Henrik Gørbitz, Ute Krengel Department of Chemistry, UiO. Crystal engineering. Biomarker identification. Protein crystallography. Molecules. H 2. ethane. sucrose. Molecules. Molecules. Crystal. Crystal. ”Crystal engineering”, we make a supermolecule!.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Carl Henrik Gørbitz, Ute Krengel
Department of Chemistry, UiO
”Crystal engineering”, we make a supermolecule!
Xe-atoms on Ni-surface (Don Eigler, 1989)Problem 1
Molecules are very small, hard to
put together one by one
As they are so small, we must put together very many before we reach a macroscopic size
A 1 x 1 x 1 mm sugar crystal
contains 1,4 · 1018 molecules
Two main types used in CE:
Fumaric acid complex
Biomarker: A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule
Present in small amounts = hard to identify
Department of Chemistry
University of Oslo