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HIV Opportunistic infections PowerPoint PPT Presentation


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HIV Opportunistic infections. OIs- 10. OIs are the most common presentation of chronic treated HIV infection. OIs– 10. No. OIs - 20. OIs usually present when CD4< 300. OIs – 20. No usually when CD4 < 200. OIs - 30. The most common OI in HIV infection. OI – 30. Oral candidiasis.

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HIV Opportunistic infections

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HIV Opportunistic infections


OIs- 10

  • OIs are the most common presentation of chronic treated HIV infection


OIs– 10

  • No


OIs - 20

  • OIs usually present when CD4< 300


OIs – 20

  • No usually when CD4 < 200


OIs - 30

  • The most common OI in HIV infection


OI – 30

  • Oral candidiasis


OI - 40

  • Name 2 of the most life threatening OIs


OI– 40

  • PCP

  • Cryptococcosis


OI- 50

  • CMV presents when CD4 < 50 and prophylaxis with antivirals should be started


OI– 50

  • Antivirals are not part of prophylaxis for HIV related OIs


PCP - 10

  • One of the most common causes of death from AIDS in 80s


PCP – 10

  • Yes


PCP- 20

  • PJP is a common environmental parasite


MHC – 20

  • IT is a fungus not a parasite


PCP- 30

  • Drug of choice for PCP prophylaxis and alternative if patient has allergy


PCP– 40

  • Diagnostic test of choice for PCP


PCP- 40

  • Diagnostic test of choice for PCP


PCP– 40

  • Sputum DFA for PCP


PCP- 50

  • One scenario that patient should stay on prophylaxis for PCP for life


PCP– 50

  • If patient had episode of PCP with CD4 > 200


Cryptococcus- 10

  • The most common manifestation of cryptococcus infection


Cryptococcus– 10

  • CNS infection


Cryptococcus- 20

  • Why frequent LPs are needed with crypto meningitis?


Cryptococcus– 20

  • Increased ICP


Cryptococcus - 30

  • Name two diagnostic tests for Cryptococcus infection


Cryptococcus– 30

  • Cryptococcus antigen

  • Fungal culture


Cryptococcus - 40

  • Name the induction therapy for Cryptococcus


Cryptococcus– 40

  • Amphotericin + 5FC


Cryptococcus - 50

  • This regimen has been used in resource poor countries for treatment of Cryptococcus infection


Cryptococcus– 50

  • High doses fluconazole (>800 mg) plus 5FC


Toxoplasma- 10

  • Name 2 presentation of toxoplasmosis


Toxoplasma- – 10

  • Fever, headaches, seizures, no clinical manifestations


Toxoplasma - 20

  • A common carrier of toxoplasma (animal)


Toxoplasma– 20

  • Cat


Toxoplasma - 30

  • The antibiotic that is used for prophylaxis for Toxoplasma is also effective for other OIs


Toxoplasma– 30

  • Bactrim is also effective against PCP


Toxoplasma- 40

  • Name alternative antibiotics for Toxoplasma (if there is allergy to the drug of choice)


Toxoplasma– 40

  • Clindamycin, pyrimethamine


Toxoplasma- 50

  • Duration of prophylaxis for toxoplasma


Toxoplasma- 50

  • Discontinue ppx when CD4>200 > 3 months


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