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HIV Opportunistic infections PowerPoint PPT Presentation


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HIV Opportunistic infections. OIs- 10. OIs are the most common presentation of chronic treated HIV infection. OIs– 10. No. OIs - 20. OIs usually present when CD4< 300. OIs – 20. No usually when CD4 < 200. OIs - 30. The most common OI in HIV infection. OI – 30. Oral candidiasis.

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HIV Opportunistic infections

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Hiv opportunistic infections

HIV Opportunistic infections


Ois 10

OIs- 10

  • OIs are the most common presentation of chronic treated HIV infection


Ois 101

OIs– 10

  • No


Ois 20

OIs - 20

  • OIs usually present when CD4< 300


Ois 201

OIs – 20

  • No usually when CD4 < 200


Ois 30

OIs - 30

  • The most common OI in HIV infection


Oi 30

OI – 30

  • Oral candidiasis


Oi 40

OI - 40

  • Name 2 of the most life threatening OIs


Oi 401

OI– 40

  • PCP

  • Cryptococcosis


Oi 50

OI- 50

  • CMV presents when CD4 < 50 and prophylaxis with antivirals should be started


Oi 501

OI– 50

  • Antivirals are not part of prophylaxis for HIV related OIs


Pcp 10

PCP - 10

  • One of the most common causes of death from AIDS in 80s


Pcp 101

PCP – 10

  • Yes


Pcp 20

PCP- 20

  • PJP is a common environmental parasite


Mhc 20

MHC – 20

  • IT is a fungus not a parasite


Pcp 30

PCP- 30

  • Drug of choice for PCP prophylaxis and alternative if patient has allergy


Pcp 40

PCP– 40

  • Diagnostic test of choice for PCP


Pcp 401

PCP- 40

  • Diagnostic test of choice for PCP


Pcp 402

PCP– 40

  • Sputum DFA for PCP


Pcp 50

PCP- 50

  • One scenario that patient should stay on prophylaxis for PCP for life


Pcp 501

PCP– 50

  • If patient had episode of PCP with CD4 > 200


Cryptococcus 10

Cryptococcus- 10

  • The most common manifestation of cryptococcus infection


Cryptococcus 101

Cryptococcus– 10

  • CNS infection


Cryptococcus 20

Cryptococcus- 20

  • Why frequent LPs are needed with crypto meningitis?


Cryptococcus 201

Cryptococcus– 20

  • Increased ICP


Cryptococcus 30

Cryptococcus - 30

  • Name two diagnostic tests for Cryptococcus infection


Cryptococcus 301

Cryptococcus– 30

  • Cryptococcus antigen

  • Fungal culture


Cryptococcus 40

Cryptococcus - 40

  • Name the induction therapy for Cryptococcus


Cryptococcus 401

Cryptococcus– 40

  • Amphotericin + 5FC


Cryptococcus 50

Cryptococcus - 50

  • This regimen has been used in resource poor countries for treatment of Cryptococcus infection


Cryptococcus 501

Cryptococcus– 50

  • High doses fluconazole (>800 mg) plus 5FC


Toxoplasma 10

Toxoplasma- 10

  • Name 2 presentation of toxoplasmosis


Toxoplasma 101

Toxoplasma- – 10

  • Fever, headaches, seizures, no clinical manifestations


Toxoplasma 20

Toxoplasma - 20

  • A common carrier of toxoplasma (animal)


Toxoplasma 201

Toxoplasma– 20

  • Cat


Toxoplasma 30

Toxoplasma - 30

  • The antibiotic that is used for prophylaxis for Toxoplasma is also effective for other OIs


Toxoplasma 301

Toxoplasma– 30

  • Bactrim is also effective against PCP


Toxoplasma 40

Toxoplasma- 40

  • Name alternative antibiotics for Toxoplasma (if there is allergy to the drug of choice)


Toxoplasma 401

Toxoplasma– 40

  • Clindamycin, pyrimethamine


Toxoplasma 50

Toxoplasma- 50

  • Duration of prophylaxis for toxoplasma


Toxoplasma 501

Toxoplasma- 50

  • Discontinue ppx when CD4>200 > 3 months


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