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Anthony Catalano. Biosensors. What are Biosensors?. Any device that analyzes a biological compound into a measurable signal Composed of a bioreceptor, transducer, and an electronic peripheral. Composition of Biosensors.

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Biosensors

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Anthony catalano

Anthony Catalano

Biosensors


What are biosensors

What are Biosensors?

  • Any device that analyzes a biological compound into a measurable signal

  • Composed of a bioreceptor, transducer, and an electronic peripheral


Composition of biosensors

Composition of Biosensors

  • Bioreceptor: Part of device that interacts with a biological material to identify and interact with a target molecule

  • Transducer: Part of the device that turns the target molecule into a measured signal

  • Electronic Peripheral: Turns the measured signal into a graphical user interface (GUI) utilizing microprocessors

  • Enzymes, Antibodies, or nucleic acids.

  • Piezoelectric, Thermal, Electrochemical, and Optical

  • LED Display


Transducers

Transducers

  • Piezoelectric: crystal detector uses the change of frequency to calculate change in mass

  • Thermal: measures change in heat (exothermic, endothermic)

  • Electrochemical: (Amperometric, or potentiometric) uses electrodes to measure current

  • Optical: uses Surface Plasmon Resonance (SPR), or reflectance to identify various biological molecules

  • Measures Mass

  • Measures heat, requires large sample size, complicated devices

  • Amperometric are among the most common transducers for biosensors

  • Great for identifying antigens, or cancerous cells in a solution


Current applications and areas of improvement

Current Applications and Areas of Improvement

Current Applications

  • Lab-on-a-chip

  • Pollutant Control

  • Patient Diagnosis

  • Detection of harmful pathogens, bacteria, toxic compounds

Future

  • Disposable

  • Low Cost

  • Increased Sensitivity

  • Improved Microprocessors

  • Multipurpose

  • Environmental friendly


Resources

Resources

1. Pohanka, Miroslave. "Electrochemical

Biosensors – Principles and Applications."

Journal of Applied Biomedicine (2008): 58-62.

Web. 20 Nov. 2012.

2. Mutharasan, Raj. "Biosensors." Engineering

Biotechnology. N.p., n.d. Web. 20 Nov. 2012.

<http://www.gatewaycoalition.org/files/Hidde

n/sensr/ch1/1_1f.htm>.

3. Kumar, Ashok. "Biosensors Based on

Piezoelectric Crystal Detectors: Theory and

Application." Department of Mechanical

Engineering and Center for Microelectronics

Research (2010): 1-6. Web.

http://www.tms.org/pubs/journals/JOM/0010/

Kumar/Kumar-0010.html

4. Dey, D., and T. Goswami. "Optical Biosensors:

A Revolution Towards Quantum Nanoscale

Electronics Device Fabrication." Journal of

Biomedicine and Biotechnology 2011.348218

(2011): 0-7. Web. 20 Nov. 2012.

<http://http://www.hindawi.com/journals/jbb

/2011/348218/>.


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