Evaluation of Corneal Graft Profile Following Deep Anterior and Posterior Lamellar Keratoplasty Procedures by Fourier-Domain Optical Coherence Tomography. Miss Tarang Gupta MB BS MRCOphth Mr Dipak Parmar BSc (Hons), MB BS(london) FRCOphth (UK).
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Evaluation of Corneal Graft Profile Following Deep Anterior and Posterior Lamellar Keratoplasty Procedures by Fourier-Domain Optical Coherence Tomography
Miss Tarang Gupta MB BS MRCOphth
Mr Dipak Parmar BSc (Hons),
MB BS(london) FRCOphth (UK)
There are no financial disclosures for this study
1. BA Noble et al Deep Anterior Lamellar Keratoplasty (DALK) Visual Outcome and Complications for a Heterogeneous Group of Corneal Pathologies Cornea 2007;26:59–64
2. Price FW, Price MO. Descemet’s stripping with endothelial keratoplasty in 200 eyes: early challenges and techniques to enhance donor adherence. J CataractRefract Surg. 2006;32(3):411-418
1.Anwar M, Teichmann KD. Big-bubble technique to bare Descemet’s membrane in anterior lamellar keratoplasty. J Cataract Refract Surg 2002;28:398–403
2.Melles GRJ, Lander F, Rietveld FJR, et al. A new surgical technique for deep stromal anterior lamellar keratoplasty. Br J Ophthalmol. 1999;83: 327–333.
Table 1 illustrates DALK patient characteristics
No of Patients
Graph 1 illustrates the change in best spectacle correct visual acuity (BSCVA) between pre operative and last post operative evaluation
Graph 2 shows the change in corneal lamellar thickness over time
Serial OCTs of a patient with a central herpetic scar undergoing DALK
Table 2 illustrating complications and management
Table 3 comparing mean change in lamellar thickness with time
Graph 3 illustrates change in various corneal lamellae with time
Serial change in DSEK lamella with time
Correlation between a) central corneal thickness and best spectacle corrected visual acuity (BSCVA) 6 months after DSEK and b) between peripheral thickness and BSCVA
Pearson correlation coefficient r = 0.54
Pearson correlation coefficient r = 0.39
Benefits of OCT Imaging
Viscoelastic in angle
Clear angle post washout/synechiolysis
1. Pascuale et al Corneal Deturgescence after Descemet Stripping Automated Endothelial Keratoplasty Evaluated by Visante Anterior Segment Optical Coherence Tomography Am J Ophthalmol 2009;148:32–37.
2. Yoo et al One-Year Results and Anterior Segment Optical Coherence Tomography Findings of Descemet Stripping Automated Endothelial Keratoplasty Combined With Phacoemulsification Arch Ophthalmol. 2008;126(8):1052-1055