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مرض السكري والنشاط البدني PowerPoint PPT Presentation


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مرض السكري والنشاط البدني. Diabetes mellitus. السُّكَّري أو الداء السكري أو المرض السكري هو مرض (أيضي) مزمن Metabolic Disease يتميز بزيادة مستوى السكر في الدم Hyperglycemia نتيجة لنقص نسبي أو كامل في الأنسولين Insulin في الدم أو لخلل في تأثير الأنسولين على الأنسجة ,

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مرض السكري والنشاط البدني

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Diabetes mellitus

Diabetes mellitus

  • () Metabolic Disease Hyperglycemia Insulin ,


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  • .

  • ( ) . .

  • .


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  • .

  • :

  • hyperglycaemia) )

  • :

  • .


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  • 70 110 100

  • 8 12 120 150 100 Physiological Hyperglycaemia

  • .

  • (12 18 ) 60 70 100 " :

  • Physiological Hypoglycaemia.


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  • Insulin Anti-Insulin .

  • Glucagon Adrenaline Glucocorticoid Growth Hormone Thyroxine.

  • .

  • .


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  • 07:00 - , .

  • 07:30 - .

  • 08:00 - .

  • 09:30 - , .

  • 13:00 - , , .

  • 16:00 - ( ).

  • 16:00 - 19:00 - / .

  • 19:00 - , .

  • 21:30 - , / .

  • 03:00 - .


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  • -

  • -""


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  • ( )

  • .


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!


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  • :

  • .

  • .

  • .

  • . .


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  • -

  • (Insulin Dependent Diabetes Mellitus) IDDM)) :

  • .


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  • -

  • Non- Insulin Dependent Diabetes Mellitus) ) ( NIDDM) :

  • .


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  • - .


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,

:

, , .

()


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  • . .

  • .


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  • beta

  • alpha


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  • Beta cells

  • .


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  • . ( ) ( ).

  • . ( ).

  • .


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  • Islets of Langherhans Beta Cells Pancreas

  • C Peptide 50% .


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  • 1.

  • .

  • 2. .

  • .


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  • . . ( ) 100% 25% .

  • KCNJ11 (

  • ATP

  • ( KCF7L2 )

  • ( ) .


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  • . .

  • . ( ) . .


Complications

Complications

  • Diabetic Nephropathy.

  • Peripheral Neuropathy.

  • Autonomic Neuropathy.

  • Atherosclerotic Cardiovascular Disease.

  • Peripheral vascular disease.

  • Cerebrovascular Disease.

  • Hypertension.

  • Dyslipidemias.

  • Psychosocial Dysfunction


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2-4

75%

- 16%

- 50%

15%


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  • , . - . .

  • , .

  • . , . .

  • . . .


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  • , . .

  • ,

  • . .

  • . .


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.

II I ,

** . .


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  • **


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( 1)

.

.

.

.

.

.


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( 2)

  • :

    • .

    • (Glu T4) .

    • .

.

.

.

.


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