Cjd and kuru prion viruses
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CJD and Kuru: Prion Viruses. By: Danny Nemeth. Prion. infectious agent composed of protein in a misfolded form. CJD. Creutzfeldt-Jakob Disease neurodegenerative disorder year of onset of illness. Structure. no Nucleic acids mass of 27,000 - 30,000 daltons 145 amino acids

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Cjd and kuru prion viruses

CJD and Kuru: Prion Viruses

By: Danny Nemeth


Prion
Prion

  • infectious agent composed of protein in a misfolded form


CJD

  • Creutzfeldt-Jakob Disease

  • neurodegenerative disorder

  • year of onset of illness


Structure
Structure

  • no Nucleic acids

  • mass of 27,000 - 30,000 daltons

  • 145 amino acids

  • Structure unknown


Cause
Cause

  • promotes refolding of native proteins

  • mass of misfolded proteins disrupts cell function



Symptoms
Symptoms

  • Neurological

    • Depression

    • Confusion

    • loss of coordination and balance

    • progressive blindness


Transmission
Transmission

  • GENETICS!

  • Defective HGH

  • CANNIBALISM!


KURU

  • Misfolded Proteins

  • Cannibalism

    • Brains


Symptoms1
Symptoms

  • Coordination problems

  • Difficulty walking

  • Swallowing difficulty

  • Tremors and muscle jerks


Treatment and prognosis
Treatment and Prognosis

  • NONE! 

  • Prognosis

    • Death after 1 year of symptoms


Stuff i used
Stuff I Used

  • http://www.cjdsurveillance.com/abouthpd.html

  • http://www.cdc.gov/ncidod/dvrd/cjd/index.htm

  • http://en.wikipedia.org/wiki/Kuru_(disease)

  • http://en.wikipedia.org/wiki/Creutzfeldt%E2%80%93Jakob_disease

  • http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002355/


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