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Immunity and Infection. Chapter 17. Chain of Infection. Transmitted through a chain (six links) Pathogen - disease causing microorganism Reservoir - natural environment of the pathogen: Person, animal or environmental component Portal of Exit Means of transmission
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Immunity and Infection Chapter 17
Chain of Infection • Transmitted through a chain (six links) • Pathogen - disease causing microorganism • Reservoir - natural environment of the pathogen: Person, animal or environmental component • Portal of Exit • Means of transmission • Direct transmission • Indirect transmission • Portal of entry • New host • Breaking the Chain
Body’s Defense System • Physical and Chemical barriers • Skin, mucous membranes, respiratory tract • Immunulogical Defenders • Neutrophils • Macrophages • Lymphocytes • T-cells • Helper, Killer, and Suppressor • B-cells • Antibodies • Memory T and B cells
The Body’s Defense System • The Inflammatory Response. • Histamine. • Dilation of blood vessels, heat, redness, and swelling.
Body’s Defense System • Immune Response • Phase 1 – Macrophages • Phase 2 – Helper T cells multiply • Production of Killer T and B cells • Cytokines • Phase 3 – Killer T cells strike • Cell-mediated immune • Anti-body mediated immune response • Phase 4 – Last Phase – • Suppressor T-cells
Immunization • The process of ‘priming’ the body to remember an encounter with a specific antigen. • VACCINE- Introduction of a killed or weakened pathogen to stimulate the body to produce antibodies. (active immunity). • PASSIVE IMMUNITY- Injection of antibodies produced by other human beings or animals. • ACQUIRED IMMUNITY-The ability of a memory lymphocytes to remember a previous infection. (chicken pox).
Allergy • The Body’s Defense System Gone Haywire • Allergies • Allergens • Pollen, Dander, Dust mites, Molds, Food, Insects • The Allergic response • Immunoglobulin (IgE) • Anaphylaxis
Dealing With Allergies • Avoidance • Medication • Immunotherapy
Type of Pathogens • Bacterium – Microscopic single celled organism • Pneumonia • Meningitis • Strep Throat and other streptococcal infections • Toxic shock and other staphylococcal • Tuberculosis • Lyme Disease • Ulcers • Antibiotic Treatment
Type of Pathogens • Viruses • Common Cold • Influenza • Measles, Mumps and Rubella • Chickenpox, Cold Sores • Other Herpes virus infections • Viral encephalitis • Viral Hepatitis • Poliomyelitis • Rabies • Warts • Treatment
Types of Pathogens • Fungus – • Primitive plant – Yeast infections, athletes foot • Protozoan – • Microscopic single-celled animal – Malaria, African sleeping sickness. • Parasitic worm – • Largest organism that can enter the body – Tapeworm, Hookworm, and Pinworm. • Prions - • Fetal degeneration disorders of the CNS, linked to “proteinaceous infectious partilces.
Emerging Infectious Diseases • Drug Resistance • Poverty • The breakdown of public health measures • Environmental changes • Travel and Commerce • Mass food production and Distribution • Human Behaviors
Other Immune Disorders • Cancer and Autoimmune Diseases • If the immune system breaks down • Getting older • HIV infection • Chemotherapy • Autoimmune diseases • Rheumatoid arthritis • Systemic lupus erythmatosus
Giving Yourself a Fighting Chance • How to support your immune system • Public Health • Taking care of yourself • Nutrition • Exercise • Rest • Moderation of Lifestyle • Controlling Stress