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The ACRIN Accrual Project at University of Washington Constance Lehman, MD. PhD David Mankoff, MD. PhD Tiffany Wong, MS PowerPoint PPT Presentation


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The ACRIN Accrual Project at University of Washington Constance Lehman, MD. PhD David Mankoff, MD. PhD Tiffany Wong, MS. Key Barriers to Accrual for ACRIN Trials:. Difficulty assigning staff for protocol start-up Difficulty identifying and consenting patients prior to therapy

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The ACRIN Accrual Project at University of Washington Constance Lehman, MD. PhD David Mankoff, MD. PhD Tiffany Wong, MS

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The ACRIN Accrual Project at

University of Washington

Constance Lehman, MD. PhD

David Mankoff, MD. PhD

Tiffany Wong, MS


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Key Barriers to Accrual for ACRIN Trials:

  • Difficulty assigning staff for protocol start-up

  • Difficulty identifying and consenting patients prior to therapy

  • Delay in start-up due to scientific and IRB reviews

  • Delay in completing qualifying procedures for start up


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A dedicated ACRIN coordinator for study start-up, maintenance and accrual support.

Support for junior faculty actively engaged in ACRIN committees and clinical trials.

A local institutional website as a resource for UW/SCCA ACRIN investigators.

Main Components of the Accrual Project:


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Increases the efficiency and speed of study activation, while decreasing the burden on site PIs.

Provides support to site PIs and junior faculty.

Provides support for ongoing trial maintenance.

Coordinates resources for start-up and study accrual using a site-specific website.

Integrates imaging into oncology practice at the trial center.

How the Accrual Project Addresses the Barriers


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ACRIN Accrual Project Coordinator

Accrual Support

Project Coordination

Data Coordination

Back-up Support

Administrative Support

  • Attends tumor board.

  • Maintains communication

  • with clinic coordinators

  • and clinicians to identify

  • participants.

  • ACRIN Trials:

  • 6684

  • 6685

  • 6689

  • Serves as primary

  • coordinator for a trial

  • by providing support on

  • all aspects of project

  • activities.

  • ACRIN Trial:

  • 6685

  • Assists transfer of

  • image files to ACRIN.

  • Ensures protocol

  • compliance of

  • technologists.

  • Receives patients and

  • collects form data at the

  • imaging appointments.

  • ACRIN Trials:

  • 6684

  • 6685

  • 6689

  • 6695

  • Assists ACRIN trial

  • primary coordinators in

  • conducting study

  • activities.

  • Serves as a back-up when

  • primary coordinators are

  • not available.

  • ACRIN Trials:

  • 6671

  • 6684

  • 6689

  • 6695

  • Assists new scanner

  • qualification.

  • Develops local ACRIN

  • website.

  • Organizes local

  • site meetings for ACRIN

  • trials.

  • Sets up centralized data

  • transfer mechanism.

  • Assists faculty who are

  • interested in starting an

  • ACRIN trial.

Responsibilities of Project Coordinator


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Project status of ACRIN Trials at UW


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Future Website for the UW-ACRIN Accrual Project


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Summary

  • The ACRIN accrual project coordinator provides supplemental staffing support for P.I.’s and junior faculty in study start-up, maintenance and accrual.

  • The accrual coordinator can serve as a central contact for multiple projects; and as a liaison between the academic center and ACRIN.

  • A local ACRIN website is a clearinghouse for essential institution-specific study development tools.

  • The UW ACRIN Accrual Project is a model system that addresses the unique barriers to research common to large academic centers.


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