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Supplemental Data

Supplemental Data. Supplement 1: Allele Frequency R 2 , Copy Number R 2 , and Mutation Percent Concordance for all samples in each tumor. Supplemental Data 2. Allele Frequency Plots for all tumors. Patient 1. Ca1 MATH = 22 Ca2 MATH = 20. Patient 4. Ca1 MATH = 7 Ca2 MATH = 9. Patient 11.

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Supplemental Data

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  1. Supplemental Data

  2. Supplement 1: Allele Frequency R2, Copy Number R2, and Mutation Percent Concordance for all samples in each tumor

  3. Supplemental Data 2 • Allele Frequency Plots for all tumors

  4. Patient 1 Ca1 MATH = 22 Ca2 MATH = 20

  5. Patient 4 Ca1 MATH = 7 Ca2 MATH = 9

  6. Patient 11 Ca1 MATH = 11 Ca2 MATH = 11 Ca3 MATH = 11

  7. Patient 20 Ca1 MATH = 42 Ca2 MATH = 40 Ca3 MATH = 40

  8. Patient 204 Ca1 MATH = 22 Ca2 MATH = 16

  9. Patient NP1 Ca1 MATH = 24 Ca2 MATH = 14 Ca3 MATH = 19

  10. Supplemental Data 3 • Copy Number Changes in all samples.

  11. TuScan Ploidy: 4 TuScan %aberrant: 55%

  12. TuScan Ploidy: 4 TuScan %aberrant: 40%

  13. TuScan Ploidy: NA TuScan %aberrant: NA 57%

  14. TuScan Ploidy: 2 TuScan %aberrant: 70%

  15. TuScan Ploidy: 2 TuScan %aberrant: 65%

  16. TuScan Ploidy: 2 TuScan %aberrant: 65%

  17. TuScan Ploidy: NA TuScan %aberrant: NA 45%

  18. TuScan Ploidy: 2 TuScan %aberrant: 55% 70%

  19. TuScan Ploidy: 4 TuScan %aberrant: 80% 90%

  20. TuScan Ploidy: NA TuScan %aberrant: NA 50%

  21. TuScan Ploidy: NA TuScan %aberrant: NA 40%

  22. TuScan Ploidy: NA TuScan %aberrant: NA 30%

  23. TuScan Ploidy: NA TuScan %aberrant: NA 45%

  24. TuScan Ploidy: 2 TuScan %aberrant: 50% 66%

  25. TuScan Ploidy: NA TuScan %aberrant: NA 45%

  26. Supplemental Data 4 • SciClone plots

  27. P1: Three individual subclones were identified in the 2 copy number state and are all in both spatially distinct samples.

  28. P4: Three individual subclones were identified in the 2 copy number state and are all in both spatially distinct samples.

  29. P11: Six individual subcloneswere identified in the 2 copy number state. Subclones 1 and 2 are shared between samples but subclones 3 and 4 are just in sample 1, subclone 5 is just in sample 2 and subclone 6 is just in sample 3.

  30. P20: Eight subclones were identified in the 2 copy number state and they were shared between samples.

  31. P204: Two subclones were identified in the 2 copy number state and they were shared between samples but more prevelent in Sample 1 than 2.

  32. NP1: Three subclones were identified in the 2 copy number state and all are shared between the different tumor samples.

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