1 / 21

Quantitative & qualitative analysis of RCT from India

Quantitative & qualitative analysis of RCT from India . Introduction: .

carr
Download Presentation

Quantitative & qualitative analysis of RCT from India

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Quantitative & qualitative analysis of RCT from India

  2. Introduction: • To consolidate and sustain the growth of the profession in the developing countries, it is essential to demonstrate that PT interventions are of high quality and cost effective Community is unique- cultural, social, customs.* • Randomized controlled trials and systematic reviews of randomized controlled trials are considered the best sources of evidence about the effects of interventions. * Robertson VJ. A quantitative analysis of research in Physical Therapy. Phys Ther. 1995; 75:315327.

  3. Objective: • The aim of the study is to locate the number of randomized controlled trial published from India and to analyze its quality.

  4. Methods: • Inclusion criteria: -all the studies in the Medline database from the time period 2000-May’13 -PT author • Exclusion criteria: -studies not relevant to PT (MEDLINE inclusion are based on considerations of both scientific policy and scientific quality. http://www.nlm.nih.gov/pubs/factsheets/jsel.html)

  5. keyterms used are “India”,”Indian” and “Physiotherapy”

  6. Parameters for Analysis: Quantitative Qualitative • Symptomatic/Asymptomatic • Clinical condition • Area of focus • Author’s affiliation • Year • Region • Core journal publications. • PEDro & CONSORT items • ‘a priori’ sample size calculation • Outcomes based on ICF domains • Explanation of the intervention • CONSORT flowchart • Reporting of ‘adverse effects’ • Statement of Primary & secondary outcome measures. • RCT in title • Funding

  7. RESULTS:

  8. Quantitative: Year trend

  9. Salient finding:

  10. PEDro:

  11. PEDro.. • Median & mode of PEDro score-5(out of 10) • Allocation concealment: 28.3% • Baseline : 73.9% • Assessor blinded : 19.6%

  12. Yearly Mean score Of PEDro:

  13. Domains: • ICF domains • Impairment -95% • Activity -32% • Participation -24%

  14. Sample size calculation: (hit or miss) • Sample size- 26.8% • Type 1 & 2 error(alpha & beta). • False positive & False negative. • Ref:Latif et al;Sample size calculation in physical medicine and rehabilitation: a systematic review of reporting, characteristics, and results in randomized controlled trials.Arch Phys Med Rehabil. 2011 Feb;92(2):306-15. doi: 10.1016/j.apmr.2010.10.003.

  15. Explanation of Intervention: • Explanation of intervention- 78% Explained Not-Explained source:Ajimsha et al source:Pattanshetty et al Arch Phys Med RehabilVol 93,April 2012 Ind journal of Med sci;2011 . If trial reports do not have a sufficient description of interventions, other researchers cannot build on the findings, and clinicians and patients cannot reliably implement useful interventions. Ref:BMJ 2013;347:f3755

  16. CONSORT flowchart(patient flow):

  17. Other quantitative findings: • Trial registry:11.6% • Reports of adverse effects:36.4% • Statement of Primary outcome measures:37.2% • RCT in title: 40% • Funding of study: 20%

  18. Discussion & Conclusion: • The trend of slope is UPWARDS. • Most of the study participants are SYMPTOMATIC(81%). • Needs to be focused on area such as knee OA, cardiovascular diseases, stroke, and others. • Future clinical trials from all regions especially eastern and western regions might increase context specific studies.

  19. Discussion(contd)… • Average!? PEDro of 5 implies the average quality of study published. Future studies need to focus on improving the quality of study design. • Patient centric outcome measures need to be considered. • A comprehensive explanation about the intervention is essential for applicability in the clinical setting. • Trial registry insist to follow the CONSORT guidelines thus enabling to report the trial effectively in a more applicable way.

More Related