ELIGIBILITY: MRC/BHF Heart Protection Study. Increased risk of CHD death due to prior disease: Myocardial infarction or other coronary heart disease; Occlusive disease of non-coronary arteries; or Diabetes mellitus or treated hypertension Age 40-80 years
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VITAMINS: COGNITIVE IMPAIRMENT(TICS-m <22/39) at Final Follow-up
SIMVASTATIN: COGNITIVE IMPAIRMENT(TICS-m <22/39) at Final Follow-up
LDL thirdSIMVASTATIN: MAJOR VASCULAR EVENT in upper & lower thirds of baseline LDL
% with major vascular events
Average LDL cholesterol (mmol/l)