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前突觸區 (presynaptic terminal) 內含有神經傳導物質 粒線體 及其它胞器 後突觸區 (postsynaptic terminal) 其上有神經傳導物質的受體 PowerPoint PPT Presentation


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突觸. 前突觸區 (presynaptic terminal) 內含有神經傳導物質 粒線體 及其它胞器 後突觸區 (postsynaptic terminal) 其上有神經傳導物質的受體 當前突觸端釋放出神經傳導物質之後 這些化學物質便利用擴散的方式抵達後突觸區 並且和其上的受體相互結合 此時將引發一個動作電位 使得這個訊號得以傳到下一個神經細胞上. 髓鞘質 將軸突裡面傳輸的訊息絕緣。膠質支持細胞製造髓鞘質。髓鞘質包裹著軸突並幫助電子流到軸突(就如同漏水的水管纏上膠帶就可以讓水在水管中流動一樣)。

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前突觸區 (presynaptic terminal) 內含有神經傳導物質 粒線體 及其它胞器 後突觸區 (postsynaptic terminal) 其上有神經傳導物質的受體

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Presynaptic terminal postsynaptic terminal


Presynaptic terminal postsynaptic terminal

(presynaptic terminal)

(postsynaptic terminal)


Presynaptic terminal postsynaptic terminal

0.22mm


Presynaptic terminal postsynaptic terminal

1/5000


Presynaptic terminal postsynaptic terminal

Multiple Sclerosis MS)

myelin''Sclerosis''skleros

33%MS100%MS


Presynaptic terminal postsynaptic terminal

  • pass


Presynaptic terminal postsynaptic terminal

-70

70(-70mV)70


Presynaptic terminal postsynaptic terminal

()

:

:

:-50-100mV

: -70mV

:

1.K+HPO42-

Na+Ca+Cl-

2.

3. >

:


Presynaptic terminal postsynaptic terminal

()

:

:

Na+Na+

-65(-70)mV-55mV

:

Na+Na+


Presynaptic terminal postsynaptic terminal

: K+K+K+


Presynaptic terminal postsynaptic terminal

:Na+Na

:K+K

1.

Na+

2.(All or None Law)

stand by

3.

:(

)


Presynaptic terminal postsynaptic terminal


Presynaptic terminal postsynaptic terminal

(action potential) (polarization)axon()

(depolarization)(-70mV)+30mV

(repolarization)

(hyperpolarization)(-70mV)(Na-K pump) (-70mV)


Presynaptic terminal postsynaptic terminal

(ACh)(DA)

(NE)(5-HT)

- Gamma-aminobutyric acid (GABA)

Glycine GlutamateAspartate


Presynaptic terminal postsynaptic terminal

Neuroactive bradykininbeta-endorphin

bombesincalcitonin

holecystokinin

enkephalindynorphin

gastrinsubstance

Pneurotensin

glucagon

secretin somatostatin

motilin


Presynaptic terminal postsynaptic terminal

vasopressin;ADHoxytocinprolactinPRLthyrotropin angiotensin IIgalaninneuropeptide Y(NPY)thyrotropin(thyroid)-releasing hormonegonadotropnin-releasing hormone(GNRH)growth hormone-releasing hormoneluteinizing hormone LHvasoactive intestinal peptide VIP;

NOCO

Bradykinin-->glutamate


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