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What are we talking about?

What are we talking about?. Functional gastrointestinal disorders (FGIDs) are defined as a variable combination of chronic or recurrent gastrointestinal symptoms not explained by structural or biochemical abnormalities.

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What are we talking about?

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  1. What are we talking about? Functional gastrointestinal disorders (FGIDs) are defined as a variable combination of chronic or recurrent gastrointestinal symptoms not explained by structural or biochemical abnormalities.

  2. …..We should focus on identifying ‘‘key’’ features or symptoms that characterize functional pain, and promote a positive diagnosis rather than a diagnosis of exclusion.

  3. What are we talking about? ….indeed, the criteria were designed to be used as diagnostic tools

  4. 243 children (4-18 yr-old): 122 Pain Predominant-FGID All underwent diagnostic investigations: 92% Lab examinations; 38.5% GI contrast radiograph studies; 23% Abdominal US; 7% CT/MRI; 33.6% Upper GI endoscopy; 17% colonoscopy Total costs: 744726 $ Cost/patient: 6104 $ JPGN 2010

  5. Is it possible to save money maintaining a high diagnostic accuracy and cost/effective treatment?

  6. AIMS: • To demonstrate that functional gastrointestinal disorders (FGIDs) can be diagnosed in a positive fashion and managed by family pediatricians (FPs); • to assess the compliance of FPs with a predefined diagnostic/therapeutic protocol for managing FGIDs in order to evaluate efficacy of continuing medical education; • to evaluate the success of reassurance by using a biopsychosocial model in comparison to drug treatment in an open-label, nonrandomized study.

  7. Methods • Twenty-one FPs from Western Sicily participated in the study • Seminar held by a senior gastroenterologist to discuss Rome criteria and a validated questionnaire • During a 3-month period FPs completed the questionnaire for all consecutive 1d-14yr old children who fulfilled Rome II criteria recording all children examined per day

  8. Pediatric FGID in Rome II classification

  9. Methods • Twenty-one FPs from Western Sicily participated in the study • Seminar held by a senior gastroenterologist to discuss Rome criteria and a validated questionnaire • During a 3-month period FPs completed the questionnaire for all consecutive 1d-14yr old children who fulfilled Rome II criteria recording all children examined per day • FPs were asked to follow the diagnostic/therapeutic protocol and in order to assess their compliance to record investigations and treatment prescribed

  10. Definition of compliance with diagnostic and therapeutic protocols

  11. Definition of compliance with diagnostic and therapeutic protocols

  12. Red flags • Epigastric or lower abdominal pain • Dysphagia • Arthritis or unexplained fever • Vomiting (once a week or more) • Gastrointestinal bleeding • Diarrhea and weight loss • Poor growth or pubertal delay • Perianal lesions • Family history of CD, IBD or peptic ulcer

  13. Definition of compliance with diagnostic and therapeutic protocols

  14. Methods • Each child who received a diagnosis of FGIDs was then re-evaluated through a standard sheet, by the same pediatrician after 1, 6 and 12 months to determine if there had been a change in diagnosis and to evaluate symptoms • Gold standard for diagnosis was clinical status at 12-month follow-up

  15. RESULTS • A total of 9291 patients, aged birth to 14 years, were prospectively enrolled; 261 met Rome II criteria and were included in the study. • In all cases but 4, diagnosis of FGIDs was confirmed at the end of follow-up (98.4%). • Average compliance of FPs was 80%. • Among 56 patients treated only with the explanation of symptom and reassurance, 52 (92.8%) have reported success, in comparison with 26 of 35 patients (74.3%) treated with drugs (odds ratio: 4.5 [95% confidence interval: 1.3–16]).

  16. Comparison of costs between two studies utilizing different diagnostic approach

  17. Is it possible to replicate this study in other settings with higher prevalence of organic diseases?

  18. 80 consecutive Chinese children ages 7 to 16 with FD • 2 groups: without any alarm features • wth alarm features • All underwent upper endoscopy • Alarm features relevant to dyspepsia: • gastrointestinal blood loss • dysphagia • persistent vomiting, persistent right upper quadrant pain, • nocturnal pain • family history of PUD and involuntary weight loss

  19. We believe that it may even be more cost-effective to perform screening tests of H pylori on male patients The study does not suggest that a negative endoscopy improves the outcome of children with FGIDs

  20. Is it possible to replicate this study in other settings with higher prevalence of organic diseases?

  21. Is it possible to replicate this study in other settings with higher prevalence of organic diseases? Is it possible or necessary to create a network with family pediatricians or general practioners?

  22. OBJECTIVE—The objectives of this study were to (1) compare the cost of medical evaluation for children with functional abdominal pain or irritable bowel syndrome brought to a pediatric gastroenterologist versus children who remained in the care of their pediatrician

  23. Is it possible to replicate this study in other settings with higher prevalence of organic diseases? Is it possible or necessary to create a network with family pediatricians or general practioners? Is it possible to apply the protocol for out or in-patients in the hospital?

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