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Mitosis & Meiosis Thurs 10/10/13. finish digestion end of lecture outline on “Role of Macromolecules” posted online; cover on your own Chromosomes & DNA homologous chromosomes / sister chromatids Cell cycle Mitosis - cellular division growth & repair

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slide1

Mitosis & Meiosis Thurs 10/10/13

  • finish digestion
    • end of lecture outline on “Role of Macromolecules” posted online; cover on your own
  • Chromosomes & DNA
    • homologous chromosomes / sister chromatids
  • Cell cycle
  • Mitosis - cellular division
    • growth & repair
  • Meiosis - sexually reproducing species
    • production of gametes (eggs & sperm)
slide2

Mitosis: process of cellular division

  • Meiosis:
    • special type of cell division
slide3

Terminology:

  • Chromosomes
    • 46 in each body cell - EXCEPT gametes
        • diploid -
        • haploid -
      • 22 pairs of homologous chromosomes (autosomes)
      • 1 pair of
    • duplication of DNA --
      • sister chromatids
slide4

Humans have 22 pairs of autosomes and 1 pair of sex chromosomes.

  • karyotype:
  • chromosomes are in
slide5

Chromosomes:

page 84

  • ~40% DNA & 60% proteins
  • contains genes
  • 23 pairs of chromosomes (46)
    • each member
  • duplication of chromosomes prior to cell division
slide7

DNA replication necessary prior to cell division

  • Replication of DNA
  • unzip strands
  • precise copying
slide8

Cell Cycle: mitosis

  • normal
  • cell divides
  • some will
  • some go off and carry out
  • cancer –

fig 5.4

slide10

Meiosis: formation of gametes

  • adults -
  • gametes (egg & sperm)
  • fertilization
  • fertilized ovum

fig5.14

  • growth & development
slide11

Meiosis:

  • DIPLOID organisms -
  • homologous pairs
  • providing each daughter cell
  • when gametes fuse

fig 5.8

  • will go through stages in lab
  • learn the sequence & importance of the events
  • will not test on specific names of stages
slide12

The Process of Meiosis: Meiosis I

diploid ---> haploid: h

fig.15.9

slide13

The Process of Meiosis: Meiosis II

haploid --->

  • cells have
  • chromosomes
  • sister chromatids
  • sister chromatids
    • total
  • daughter cells

fig.15.12

slide14

Sources of Genetic Variation:

  • Crossing over during Meiosis I
  • exchange of alleles
  • swapping of the

fig5.10

  • alleles
slide15

Sources of Genetic Variation:

  • independent assortment of chromosomes during meiosis I

figure15.11

slide16

Sources of Genetic Variation:

  • Independent assortment
  • Random Fertilization!
    • 8+ million possible
    • 8+ million possible
slide18

Mitosis vs. Meiosis

  • Mitosis
  • Meiosis

Be comfortable with figure5.13

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