Mitosis & Meiosis
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Mitosis & Meiosis Thurs 10/10/13. finish digestion end of lecture outline on “Role of Macromolecules” posted online; cover on your own Chromosomes & DNA homologous chromosomes / sister chromatids Cell cycle Mitosis - cellular division growth & repair

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Mitosis & Meiosis Thurs 10/10/13

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Mitosis meiosis thurs 10 10 13

Mitosis & MeiosisThurs 10/10/13

  • finish digestion

    • end of lecture outline on “Role of Macromolecules” posted online; cover on your own

  • Chromosomes & DNA

    • homologous chromosomes / sister chromatids

  • Cell cycle

  • Mitosis - cellular division

    • growth & repair

  • Meiosis - sexually reproducing species

    • production of gametes (eggs & sperm)


Mitosis meiosis thurs 10 10 13

Mitosis: process of cellular division

  • Meiosis:

    • special type of cell division


Mitosis meiosis thurs 10 10 13

Terminology:

  • Chromosomes

    • 46 in each body cell - EXCEPT gametes

      • diploid -

      • haploid -

    • 22 pairs of homologous chromosomes (autosomes)

    • 1 pair of

  • duplication of DNA --

    • sister chromatids


Mitosis meiosis thurs 10 10 13

Humans have 22 pairs of autosomes and 1 pair of sex chromosomes.

  • karyotype:

  • chromosomes are in


Mitosis meiosis thurs 10 10 13

Chromosomes:

page 84

  • ~40% DNA & 60% proteins

  • contains genes

  • 23 pairs of chromosomes (46)

    • each member

  • duplication of chromosomes prior to cell division


Mitosis meiosis thurs 10 10 13

  • GENES


Mitosis meiosis thurs 10 10 13

DNA replication necessary prior to cell division

  • Replication of DNA

  • unzip strands

  • precise copying


Mitosis meiosis thurs 10 10 13

Cell Cycle: mitosis

  • normal

  • cell divides

  • some will

  • some go off and carry out

  • cancer –

fig 5.4


Mitosis meiosis thurs 10 10 13

Mitosis - cell division

Fig 5.5

fig 9.2


Mitosis meiosis thurs 10 10 13

Meiosis: formation of gametes

  • adults -

  • gametes (egg & sperm)

  • fertilization

  • fertilized ovum

fig5.14

  • growth & development


Mitosis meiosis thurs 10 10 13

Meiosis:

  • DIPLOID organisms -

  • homologous pairs

  • providing each daughter cell

  • when gametes fuse

fig 5.8

  • will go through stages in lab

  • learn the sequence & importance of the events

  • will not test on specific names of stages


Mitosis meiosis thurs 10 10 13

The Process of Meiosis: Meiosis I

diploid ---> haploid: h

fig.15.9


Mitosis meiosis thurs 10 10 13

The Process of Meiosis: Meiosis II

haploid --->

  • cells have

  • chromosomes

  • sister chromatids

  • sister chromatids

    • total

  • daughter cells

fig.15.12


Mitosis meiosis thurs 10 10 13

Sources of Genetic Variation:

  • Crossing over during Meiosis I

  • exchange of alleles

  • swapping of the

fig5.10

  • alleles


Mitosis meiosis thurs 10 10 13

Sources of Genetic Variation:

  • independent assortment of chromosomes during meiosis I

figure15.11


Mitosis meiosis thurs 10 10 13

Sources of Genetic Variation:

  • Independent assortment

  • Random Fertilization!

    • 8+ million possible

    • 8+ million possible


Mitosis meiosis thurs 10 10 13

Key Events in Meiosis:


Mitosis meiosis thurs 10 10 13

Mitosis vs. Meiosis

  • Mitosis

  • Meiosis

Be comfortable with figure5.13


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