Analgesia, Anesthesia, and Sedation Tintinalli Chap 36, 37, 38, 39. Nicholas Cardinal, DO. Acute Pain. Accompanies 50-60% of ED patient visits in U.S. and Great Britain Pain The physiologic response to a noxious stimulus Accentuated by fear and anxiety Affected by many factors
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Analgesia, Anesthesia, and SedationTintinalli Chap 36, 37, 38, 39
Nicholas Cardinal, DO
Analgesic and anti-inflammatory
Have significant opioid dose-sparing effects
Adverse effects include platelet dysfunction, impaired coagulation, and gastrointestinal irritation and bleeding
Acute Renal Failure in elderly, volume depleted