NPM1 c L287Fs* (insTCTG). FLT3 D835Y. DNMT3A R882C. P1. NF1 intron 2. ASXL1 G642fs*. KRAS K117N. TET2 L1119*. P2. CEBPA T310NT. CEBPA A111fs*. NRAS G12D. WT1 R145fs*. P3. P3. NPM1c L287fs* (insTCTG). IDH2 R 140Q. P4. NPM1c L287fs* (insTCTG). IDH1 R132H. FLT3 D835Y. P5.
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NPM1c L287Fs* (insTCTG)
NF1 intron 2
IDH2 R 140Q
Supplementary Figure S2. Confirmation by capillary sequencing of 21 substitutions and indels identified by targeted pull-down. Chromatographs from AML samples P1-P7 (upper) are contrasted with normal DNA (lower). Arrows indicate substitutions and arrowhead indicate indels.