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MR Imaging of the Brain. Radiology 401. John R. Hesselink, M.D. MR System Components. Transmitter. Gradient Amplifier. RF Coil. Gradient. Computer. Gradient. RF Coil. Magnet. Receiver. Digitizer. Source of Signal and Contrast. Proton density T1 relaxation time T2 relaxation time

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Mr imaging of the brain
MR Imaging of the Brain

Radiology 401

John R. Hesselink, M.D.


Mr system components
MR System Components

Transmitter

Gradient Amplifier

RF Coil

Gradient

Computer

Gradient

RF Coil

Magnet

Receiver

Digitizer


Mr imaging

Source of Signal and Contrast

Proton density

T1 relaxation time

T2 relaxation time

Flow effects

MR Imaging


RF

TR

TE

Signal

Spin-echo Pulse Sequence

Single Echo T1-weighted

1st

echo

2nd

echo


Spin echo pulse sequence

RF

TR

TE

TE

Signal

Spin-echo Pulse Sequence

Dual Echo T2-weighted

1st

echo

2nd

echo




Normal FLAIR Images

TR = 6000 msec, TI = 2000 msec, TE = 102 msec



Mr signal of brain lesions
MR Signal ofBrain Lesions


T1W

T2W

Solid

Brain

Lesion

PDW


T1W

Cystic

Lesion

FLAIR

T2W

236


Subacute

Hemorrhage

PDW

T1W

T2W


T2W

FLAIR

Acute

Hemorrhage

T1W

GRE



Hemorrhage Sequence

Gradient-echo


Fat

or

Lipoma

T2W

PDW

T1W


Mr signal intensities
MR Signal Intensities

T2WI

PD/FLAIR

T1WI

Solid mass

Bright

Bright

Dark

Cyst

Bright

Dark

Dark

Subacute blood

Bright

Bright

Bright

Acute & chronic blood

Dark

Dark

Gray

Fat

Dark

Bright

Bright


Acute Stroke Sequence

Diffusion Weighted Imaging



MR Spectroscopy

Dx: Anaplastic astrocytoma > GBM


Brain screening protocol

Axial T2-weighted images

Axial FLAIR images

If normal:

Stop

If abnormal:

T1-weighted images

Gd-DTPA enhancement

Brain Screening Protocol


History: 46 y.o. man

with headaches & increasing confusion

2

1

T2W

PDW


4

3

T1W

T1W

5

{Page 2}

T1W / Gd


Increasing confusion {Page 3}

6

7

Dx: Meningioma & right MCA infarct


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