introduction to virology
Download
Skip this Video
Download Presentation
Introduction to Virology

Loading in 2 Seconds...

play fullscreen
1 / 35

Introduction to Virology - PowerPoint PPT Presentation


  • 192 Views
  • Uploaded on

Introduction to Virology. I. Objectives. What is a virus How do viruses multiply How are viruses classified (What are some of the diseases viruses cause). II. Historical Perspective. A. Ancient times 1. poliovirus 2. smallpox B. More recent history 1. 1790’s Iwanowski 2. 1890’s

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about ' Introduction to Virology' - brede


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
i objectives
I. Objectives
  • What is a virus
  • How do viruses multiply
  • How are viruses classified
  • (What are some of the diseases viruses cause)
ii historical perspective
II. Historical Perspective
  • A. Ancient times
    • 1. poliovirus
    • 2. smallpox
  • B. More recent history
    • 1. 1790’s
      • Iwanowski
    • 2. 1890’s
      • Jenner
iii what is a virus
III. What is a virus?
  • A. Characteristics
b comparison to bacteria 1 overall
B. Comparison to bacteria1. overall
  • Bacteria Virus
  • Intracellular parasite (no) yes
  • Plasma membrane yes no
  • Binary fission yes no
  • Filterable no yes
  • Possess DNA & RNA yes no
  • ATP production yes no
  • Ribosomes yes no
  • Antibiotic sensitive yes no
slide6
2. Growth comparison
  • 3. Size comparison
  • 4. Genome size comparison
slide8
A. Helical
  • B. Polyhedral
  • C. Complex
v how viruses multiply 13 10
V. How viruses multiply (13.10)
  • 1. Basic strategy
    • Attachment
    • Penetration
    • Synthesis of viral proteins and nucleic acids
    • Maturation
    • Release
2 bacterial viruses fig 13 12
2. Bacterial viruses: Fig 13.12
  • Lytic vs lysogenic cycle
4 differences in lab culture of viruses
4. Differences in lab culture of viruses
  • a. bacteriophage
  • b. animal viruses
vi differences in multiplication due to differences in genome organization
VI. Differences in multiplication due to differences in genome organization
  • A. Genome organization
vi classification schemes
VI. Classification schemes
  • A. Formal taxonomies
  • B. Baltimore Classification
c nucleic acid type baltimore classification
C. Nucleic acid type --> Baltimore classification
  • Class I
    • ds DNA
  • Class II
    • ssDNA (positive and negative)
  • Class III
    • dsRNA
  • Class IV
    • ssRNA (positive)
slide19
Class V
    • ssRNA (negative)
  • Class VI
    • ssRNA (positive, replication intermediate DNA)
1 class i dsdna viruses
1. Class I: dsDNA Viruses
  • Bacterial
    • Bacteriophage
  • Plant
    • Caulomoviridae
slide21
Human
    • Herpesviridae
    • Adenoviridae
    • Poxviridae
    • Papovaviridae
      • Papillomavirus
      • Polyomavirus
      • Vacuolating agent
slide22
Hepadnaviridae
    • After protein synthesis, DNA replicated through RNA intermediate
2 class ii ssdna viruses
2. Class II: ssDNA viruses
  • Bacteria
  • Plant
  • Animal
4 class iv ss rna viruses
4. Class IV: ss (+) RNA viruses
  • Picornaviridae
  • Togaviridae
  • Flaviviridae
  • Coronaviridae
  • Calciviridae
5 class v ss rna viruses
5. Class V: ss (-) RNA viruses
  • Rhabdoviridae
  • Filoviridae
  • Paramyxoviridae
  • Orthomyxoviridae
  • Bunyaviridae
  • Deltaviridae
  • Arenaviridae
6 class vi ss viruses dsdna intermediate
6. Class VI: ss (+) viruses (dsDNA intermediate)
  • Retroviridae
    • Oncoviruses
    • Lentivirus
ix plant viruses
IX. Plant viruses
  • Morphologically similar to animal viruses
  • Enter through wounds or parasites
  • Some multiply in insects
x viroids
X. Viroids
  • Plant pathogens
    • infectious naked RNA
  • 20-25 identified so far
  • ss covalent circle
xi prions
XI. Prions
  • A. Fig 13.21
  • B. PrPC vs PrPSc
    • Structural differences
    • Detergent solubility differences
    • Differences in susceptibility to protein degrading enzymes
ad