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Vemurafenib: mechanisms of resistance and secondary skin tumors

US alone

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Vemurafenib: mechanisms of resistance and secondary skin tumors

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    1. Eric Knoche No financial disclosures Vemurafenib: mechanisms of resistance and secondary skin tumors

    2. US alone – 8700 deaths Median Survival: 8-18 months As of 2010, two FDA approved therapies for metastatic melanoma IL-2: response rates of 10-20%, rare complete response among responders Dacarbazine: response rates 7-12%, median survival 5.6-7.8 months

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