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Veterans Aging Cohort Study (VACS)

Veterans Aging Cohort Study (VACS). Required:. Optional based on other project funding:. Now have support through August 2016 for a total of 20 years of follow up in Virtual Cohort and 16 years for VACS 8. VACS Cohort and Substudies.

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Veterans Aging Cohort Study (VACS)

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  1. Veterans Aging Cohort Study (VACS) Required: Optional based on other project funding:

  2. Now have support through August 2016 for a total of 20 years of follow up in Virtual Cohort and 16 years for VACS 8

  3. VACS Cohort and Substudies Virtual Cohort(VC) comprised of national data. Elements include demographics, diagnostic and procedure codes, labs, pharmacy, vital signs… VACS9 is the 9 site consented patient study with richer data. Includes surveys, adjudicated outcomes for cancer, mi, liver disease, site downloaded data VC limited to patients in 2003 or later. Includes adjudicated MI from IHD Queri Includes Ddimer, IL6, sCD14 3 VACS sites only. Includes GXT, CT and echo data

  4. Virtual Cohort (VC) • SUBJECTS: 47,805 HIV infected; 99,061 uninfected • All individuals with HIV diagnoses • Age, race/ethnicity, region 2:1 matched controls • Last updated: September 2012 • Next update: September 2014 • SITES: All VA sites • BASELINE: 1998 (15 years of follow up) • HIV infected veterans at initiation of HIV care • Controls selected and followed in same calendar year

  5. VACS 9 • CURRENT DATA SOURCES (all VC sources plus) • All VA Electronic medical records including text fields • Sentinel event records (MI) requested outside VA • DNA and tissue bank • Annual self completed surveys (health behaviors, quality of life, symptoms, outside utilization, etc.) • SUBJECTS: 3790 HIV infected; 3962 uninfected • Group matched: age, race/ethnicity, and site • Last updated October 16, 2013 • SITES:Manhattan, Bronx, Washington DC, Baltimore, Pittsburgh, Atlanta, Houston, Los Angeles, Dallas • BASELINE: 2002 (11 years)

  6. National VACS Project Team 2011

  7. COMpAAAS

  8. Acknowledgements • Consortium PI : AC Justice* • Scientific Collaborator (NIAAA): K Bryant • Affiliated PIs: S Braithwaite, K Crothers*, R Dubrow *, DA Fiellin*, M Freiberg*, V LoRe* • Participating VA Medical Centers: Atlanta (D. Rimland*, V Marconi), Baltimore (M Sajadi, R Titanji), Bronx (S Brown, Y Ponomarenko), Dallas (R Bedimo), Houston (M Rodriguez-Barradas, N Masozera), Los Angeles (M Goetz, D Leaf), Manhattan-Brooklyn (M Simberkoff, D Blumenthal, H Leaf, J Leung), Pittsburgh (A Butt, K Kraemer, M Freiberg, E Hoffman), and Washington DC (C Gibert, R Peck) • Core and Workgroup Chairs: C Brandt, J Edelman, N Gandhi, J Lim, K McGinnis, KA Oursler, C Parikh, J Tate, E Wang, J Womack • Staff: H Bathulapalli, T Bohan, J Ciarleglio, A Consorte, P Cunningham, L Erickson, C Frank, K Gordon, J Huston, F Kidwai-Khan, G Koerbel, F Levin, L Piscitelli, C Rogina, S Shahrir, M Skanderson • Major Collaborators: VA Public Health Strategic Healthcare Group, VA Pharmacy Benefits Management, Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), Yale Center for Interdisciplinary Research on AIDS (CIRA), Center for Health Equity Research and Promotion (CHERP), ART-CC, NA-ACCORD, HIV-Causal • Cross Cohort Collaborators: Richard Moore (NA-ACCORD), Jonathan Sterne (ART-CC), Brian Agan (DoD), Miguel Hernan (HIV-Causal) • Major Funding by: National Institutes of Health: AHRQ (R01-HS018372), NIAAA (U24-AA020794, U01-AA020790, U01-AA020795, U01-AA020799, U24-AA022001, U24 AA022007, U10 AA013566-completed), NHLBI (R01-HL095136; R01-HL090342) , NIAID (U01-A1069918), NIMH (P30-MH062294), NIDA (R01DA035616), NCI (R01 CA173754) and the Veterans Health Administration Office of Research and Development (VA REA 08-266, VA IRR Merit Award) and Office of Academic Affiliations (Medical Informatics Fellowship) *Indicates individual is also the Chair of a Core or Workgroup

  9. AcknowledgementsContinued QR Codes QR Code for VACS QR Code for VACS QR Code for VACS Homepage INDEX CALCULATOR- INDEX CALCULATOR- MOBILE APP Other Notable Funding:Career Development Awards: Veterans Health Administration: VISN 1 CDA (V1CDA2012-20), HSR&D CDA-2 (08-276); National Institutes of Health: NINR (1K01R013437), NCRR/NCATS (5UL1RR024139), NIDA (1K12DA033312-01A1, 8UL1TR000142, 1R03DA031592) COMpAAAS/Veterans Aging Cohort Study, a CHAART Cooperative Agreement, supported by the National Institutes of Health: National Institute on Alcohol Abuse and Alcoholism (U24-AA020794, U01-AA020790, U01-AA020795, U01-AA020799; U10 AA013566-completed) and in kind by the US Department of Veterans Affairs.  In addition to grant support from NIAAA, we gratefully acknowledge the scientific contributions of Dr. Kendall Bryant, our scientific collaborator.

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