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The List of Renal Hormones ( Compliments of Patrick McL.)

The List of Renal Hormones ( Compliments of Patrick McL.). Ooohhhhhh…. What makes me have to tinkle so bad? I wish I didn’t drink all those yummy Duff’s. “These charts have so many crazy hormones, it’s like a teenage boy in a porn shop.” –Anonymous M.S. I.

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The List of Renal Hormones ( Compliments of Patrick McL.)

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  1. TheList of Renal Hormones(Compliments of Patrick McL.) Ooohhhhhh…. What makes me have to tinkle so bad? I wish I didn’t drink all those yummy Duff’s. “These charts have so many crazy hormones, it’s like a teenage boy in a porn shop.” –Anonymous M.S. I

  2. Renal baroreceptors - ( pressure) Sympathetic n. Flow in the macula densa Ang. II Renin Location of Effects: Stimulation: Effects: • Converts angiotensinogen to Ang. I

  3. Renin Aldosterone ADH Mesangial cell contraction - GFR (directly) Na+/H+ exchanger rate ( Na+ reabsorb) Renal vasocontriction RPF Angiotensin II Location of Effects: Stimulation: Effects: • Adrenal conrtex • Post. Pituitary • Glomerulus • PCT • Efferent a.

  4. Ang. II Plasma K+ ACTH Plasma Na+ - (indirectly via fluid volume.) Na+ reabsorption K+ secretion H+ secretion ADH Aldosterone Location of Effects: Stimulation: Effects: • Principle cells (CCD) • Principle cells (CCD) • Intercalated cells (IMCD) • Post. Pituitary

  5. Aldosterone Plasma osmol. (via osmoreceptors) Barorecptor activity ( BP) Pain H20 reabsorption Urea reabsorption K+ secretion ADH Location of Effects: Stimulation: Effects: • Principle cells (CCD) • Principle cells (IMCD) • Principle cells (CCD)

  6. Barorecptor activity ( BP) Afferent vasoconstriction - GFR & RPF Renin Na+ reabsorption Sympathetic N. Location of Effects: Stimulation: Effects: • Afferent a. • Juxtaglom. cells • PCT & TAL

  7. Atrial stretch receptors - ( blood vol.) Renin: - Ang. II Aldosterone: - Na+ reabsorption Afferent dilation/ Efferent constrict. - GFR Direct block of Na+ reabsorption ANF (ANP) Location of Effects: Stimulation: Effects: • Juxtaglom. cells • Adrenal cortex • Renal arterioles • Principle cells (CD)

  8. Plamsa Ca++ Ca++ reabsorption PO4- secretion - Na+/PO4-contransporter inhibited Vitamin D production PTH Location of Effects: Stimulation: Effects: • PCT, TAL & DCT • PCT (not in kidney, so don’t sweat it…yet)

  9. Disclaimer As you all should assume by now, this material was created as accurately as possible and is to the best of my knowledge correct. If there’s something in here you don’t like…then deal with it. You may or may not need to know this material in the depth I have provided for the exam; however your patients may beg to differ at some point. **If you print this out in 2 or 4 slides per page, they make great flash cards (if you’re into that kind of stuff).

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