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METABOLOMICS “bringing genomes to life.”

METABOLOMICS “bringing genomes to life.”. Shubhi. Plan to Proceed. Various instruments and approaches(MS and NMR). Study of various format of output as well as stored data , various fields in the output, etc. Filtering and cleaning of data. Introduction.

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METABOLOMICS “bringing genomes to life.”

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  1. METABOLOMICS“bringing genomes to life.” Shubhi

  2. Plan to Proceed • Various instruments and approaches(MS and NMR). • Study of various format of output as well as stored data , various fields in the output, etc. • Filtering and cleaning of data.

  3. Introduction • Metabolomics has been defined as the identification and quantification of all metabolites in a biological system . • It is becoming a tool in : • The functional annotation of genes and enzymes . • The comprehensive understanding of cellular and organism specific responses to biological, environmental and drug-related perturbations. • Network of biological systems provide such frameworks by defining links between the network components in a bottom to-top approach.

  4. Types of Data • Various types of “omics” data can be used to identify the list of network components and their interactions. • These network represent biochemically, genetically, and genomically structured databases that simultaneously integrate all component data, and can be used to visualize and analyze further , such as : gene expression metabolomicsfluxomics data Biological source

  5. Representation of Database • There are at least three ways to represent databases: • Textual representation, which allows querying of its content; • Graphical representation, which allows the visualization of the network interactions and their components; • Mathematical representation, which enables the usage of a growing number of analytical tools to characterize and study the network properties.

  6. Various Formats Of Data • To capture the required metadata, ArMet encompasses the entire experiment time line and organises it into nine subunits i.e in UML format . • The widely adopted modeling standard UML to represent ArMet. ArMet’s component are modeled as UML packages. • UML is basically used to model the key concepts for each component .

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