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Animal and Plant viruses

Animal and Plant viruses. Plate Culture of Animal Viruses. Figure 6.33. Figure 6.20. Papillomavirus (DNA) Life Cycle. Figure 6.22. Picornavirus (RNA) Life Cycle. Figure 6.23. Figure 11.15. The capsid is fundamentally icosahedral. - Composed of three external proteins (VP1–3)

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Animal and Plant viruses

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  1. Animal and Plant viruses

  2. Plate Culture of Animal Viruses Figure 6.33

  3. Figure 6.20

  4. Papillomavirus (DNA) Life Cycle Figure 6.22

  5. Picornavirus (RNA) Life Cycle Figure 6.23

  6. Figure 11.15

  7. The capsid is fundamentally icosahedral. - Composed of three external proteins (VP1–3) - VP4 protein subunits coat the interior and help package the (+) strand RNA genome. Poliovirus Structure Figure 11.11B

  8. The poliovirus binds to poliovirus receptor (PVR) through its VP2 and VP3 subunits. - A conformational change in VP1 allows insertion of the genome into the cytoplasm. Figure 11.12

  9. In the cytoplasm, the RNA is translated to make three large precursor peptides: P1–3. - All three peptides are eventually cleaved by proteases to generate 11 proteins. Poliovirus Replication Figure 11.13A

  10. The flu virus has no geometric capsid. RNA genome is loosely contained by a shell of matrix proteins. Influenza Virus Structure Figure 11.16 RNA segments are coated with nucleocapsid proteins (NPs). Two major envelope proteins: - Neuraminidase (NA) - Hemagglutinin (HA)

  11. Influenza virus: note envelope

  12. The Genome of Influenza A Virus Figure 11.17

  13. The key advantage of a segmented genome is that it facilitates recombination between two strains coinfecting the same cell. - Instant new strain can evade the immune system. Figure 11.18B

  14. Animation: Influenza Virus Entry into a Cell Influenza Virus Entry Click box to launch animation

  15. Figure 11.21

  16. Animation: Influenza Virus Replication Influenza Virus Replication Click box to launch animation

  17. An icosahedral capsid houses the dsDNA genome. Herpes Simplex Virus Structure Capsid is surrounded by a protein tegument, which is contained within an envelope with spike proteins. Figure 11.31A

  18. Figure 11.32

  19. Animation: Herpes Virus Replication Herpes Virus Replication Click box to launch animation

  20. Within a plant, the thick cell walls prevent a lytic burst or budding out of virions. - Instead, plant viruses are transmitted to uninfected cells by plasmodesmata. Figure 6.26

  21. Fig. 19-11 tRNA-like structure Stop codon Cap RNP MP CP MTH

  22. A viroid

  23. Figure 6-6 Viroids: infective RNA.

  24. Figure 6-7 Prion disease.

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