Nuclear DNA and Mitochondrial DNA. Nuclear DNA. Present in almost every cell Combination from both parents; 23 chromosomes from each parent. Mitochondrial DNA. Each cell contains thousands of mt, each containing copies of its DNA Mt DNA is in larger quantities in a cell
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Control Region regions
This region is highly variable within the human population
Consists of 2 subregions
HV1 = 342 bp HV2 = 268
610 bp with a lot of variability
Why Mom? regions
Mutations occur in the control region of mt DNA at a regular rate and are passed onto children by the mom.
How do we use this information? rate and are passed onto children by the mom.
Mitochondrial Eve rate and are passed onto children by the mom.
How is mtDNA isolated? rate and are passed onto children by the mom.
Using a database you will compare your mt DNA with: