Nuclear DNA and Mitochondrial DNA. Nuclear DNA. Present in almost every cell Combination from both parents; 23 chromosomes from each parent. Mitochondrial DNA. Each cell contains thousands of mt, each containing copies of its DNA Mt DNA is in larger quantities in a cell
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Nuclear DNA and Mitochondrial DNA
This region is highly variable within the human population
Consists of 2 subregions
HV1 = 342 bpHV2 = 268
610 bp with a lot of variability
Mutations occur in the control region of mt DNA at a regular rate and are passed onto children by the mom.
How do we use this information?
How is mtDNA isolated?
Using a database you will compare your mt DNA with: