Array CGH. Louise McClelland 10 th November 2010. Introduction. Background Technical details Applications Interpreting CNV. Key terms. Array comparative genomic hybridisation ( aCGH ) Copy number variants (CNV) Catch all term for any copy number change Copy number polymorphisms (CNP)
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
10th November 2010
Karyotyping 3-10 Mb
Investigate and report back to Regional labs for confirmation work
Most common microdeletion syndrome in Ahn et al., 2010 (15 cases, 0.62%)
“Our ability to discover genetic variation is running ahead of our ability to interpret them”
Huang et al., 2010Conclusions