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Orthomyxoviridae: human influenza viruses PowerPoint PPT Presentation


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Orthomyxoviridae: human influenza viruses. Poxviridae. Retroviridae: HIV. Enveloped viruses versus membrane-containing viruses. Alphaviruses Flaviviruses. HSV / f 6. PRD1. PM2 ?. Bacteriophage PRD1. “penton”. outer leaflet. DNA. inner leaflet. PRD1 structural proteins.

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Orthomyxoviridae: human influenza viruses

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Orthomyxoviridae human influenza viruses l.jpg

Orthomyxoviridae: human influenza viruses


Poxviridae l.jpg

Poxviridae


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Retroviridae: HIV


Enveloped viruses versus membrane containing viruses l.jpg

Enveloped viruses versusmembrane-containing viruses

Alphaviruses

Flaviviruses

HSV / f6

PRD1

PM2 ?


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Bacteriophage PRD1


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“penton”

outer leaflet

DNA

inner leaflet


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PRD1 structural proteins

P3 major coat 43 kDa x

P30 minor coat 9 kDa x

P2 receptor binding 64 kDa

P5 spike 34 kDa

P31 penton 14 kDa x

CAPSID

VERTICES

P6 portal 18 kDa

P9 packaging ATPase 26 kDa

P20 DNA packaging (M) 5 kDa

P22 DNA packaging (M) 6 kDa

PACKAGING

VERTEX

P7 transglycosylase (M) 27 kDa

P14 DNA delivery (M) 15 kDa

P15 muramidase 17 kDa

P16 infectivity (M) 13 kDa x

P18 DNA delivery (M) 10 kDa

P32 DNA delivery (M) 5 kDa

P34 (M) 7 kDa

ENTRY

(M) integral membrane protein


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Sarah Butcher


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David Stuart

Nicoal Abrescia


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Richard Kuhn


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John Briggs

Retroviruses

Asymmetric

Variable in diameter

Envelopment requires both viral and cellular proteins

Membrane plays role in both assembly and maturation


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George J Thomas

Escherichia coli


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George J. Thomas


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irido

adeno

PRD1

Lineage 1

Lineage 2

Lineage 3

phi6

BTV

herpes


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