A closer look at cell membranes. Chapter 5 Transport and other things. Reminders…. Your grades are done as follow: Class participation – in order to do that you need to check bostononline and do the readings suggested. Notebook – class notes and your own personal study notes
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A closer look at cell membranes
Your grades are done as follow:
Class participation – in order to do that you need to check bostononline and do the readings suggested.
Notebook – class notes and your own personal study notes
Workshops and special writings.
Final term test
All the classes are taken from your book…
The themes are the ones we set out to covered in the class development indicators .
From the beginning you were told to read the themes related to the lectures covered in class.
To read from the book the themes covered is part of your responsibility.
In Bostononline you find references to your book and reading to be done.
The video and presentations are done to facilitate your learning process.
Next Class Quiz and Checking your notebook
Questions to answer in the process
Review and Cell Membrane Proteins
Looking at what we saw and adding some new stuff
Cell Membrane Views
Microdomains on plasma membrane
Lipid rafts (~ 50nm)
Sphingolipids (long saturated chains)
Phospholipids in cell signaling
GEF, AKT, migrating front
Lipid molecules: phospholipids, cholesterol, glycolipid, all amphipathic
Lipid bilayer, hydrophobic inside and hydrophilic outside
Subdomains on membrane, asymmetry important for functions
Phospholipids as signals
Integral membrane protein
Peripheral membrane protein
Glycosylphosphatidylinositol (GPI) anchor protein
Fatty acid chain (acyl, N-terminal) or prenyl group modifications (C-terminal)
Membrane proteins are glycosylated
Sugar are added in the lumen of the ER and Golgi apparatus, therefore, sugar are outside of cell surface
Cytosol has reduced environment, preventing disulfide bonds
Membrane proteins are diffusible
Tight Junction is one kind of them
Proteins and lipids on the outer layers can’t move to other compartments
Looking at how the cell work live!!!!
CellMembranes and DiffusionLab