Gene panel training session
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Gene Panel Training session. Valairat Dhamcharee , M.D. Diplomate American Board of Medical Genetics Diplomate American Board of Neonatal Perinatal Medicine Diplomate American Board of Pediatrics. Take a more active role in managing your health. Goal.

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Gene Panel Training session

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Gene panel training session

Gene PanelTraining session

ValairatDhamcharee, M.D.

Diplomate American Board of Medical Genetics

Diplomate American Board of Neonatal Perinatal Medicine

Diplomate American Board of Pediatrics


Gene panel training session

Take a more active role in managing your health


Gene panel training session

Goal

  • 1.Be on the lookout for common conditions

  • 2.Prepare for serious diseases

  • 3.Prevention of the unforeseen threats

  • 4.Make better lifestyle choices

Valairat Dhamcharee, M.D.


Gene panel training session

Target group: All age

Test: Genetic markers

Method: Saliva collection by Saliva kit


Benefits

Benefits

  • Early detection

  • Prevention

  • Treatment

  • Possible reversal of age-related disorders

Valairat Dhamcharee, M.D.


Categories of testings

Categories of Testings

  • 1.Cardiovascular

  • 2.Metabolic

  • 3.Eye and vision

  • 4.Degenerative disorders

  • 5.Bones and joints

  • 6.Cancers

  • 7.Carrier status

  • 8.Drug response and side effects

Valairat Dhamcharee, M.D.


Cardiovascular

Cardiovascular

  • Abdominal Aortic Aneurysm

  • Atrial Fibrillation

  • Heart Attack

  • Hypertension

  • Peripheral Arterial Disease

  • Venous Thromboembolism

Valairat Dhamcharee, M.D.


Metabolic

Metabolic

  • Obesity

  • Type 1 Diabetes

  • Type 2 Diabetes

Valairat Dhamcharee, M.D.


Eye and vision

Eye and vision

  • Age Related Macular Degeneration

Valairat Dhamcharee, M.D.


Degenerative disorders

Degenerative disorders

  • Alzheimer’s Disease

  • Essential Tremor

  • Multiple Sclerosis

Valairat Dhamcharee, M.D.


Bones and joints

Bones and joints

  • Gout

  • Rheumatoid Arthritis

  • Osteoarthritis

Valairat Dhamcharee, M.D.


Cancers

Cancers

  • Basal Cell Carcinoma

  • Bladder Cancer

  • Breast Cancer

  • Colorectal Cancer

  • Lung Cancer

  • Ovarian Cancer

  • Pancreatic Cancer

  • Prostate Cancer

  • Testicular Cancer

  • Thyroid Cancer

Valairat Dhamcharee, M.D.


Male testings

Male testings

  • Cardiovascular

  • Metabolic

  • Eye and vision

  • Degenerative disorders

  • Bones and joints

  • Cancer: Prostate, testicular

Valairat Dhamcharee, M.D.


Female testings

Female testings

  • Cardiovascular

  • Metabolic

  • Eye and vision

  • Degenerative disorders

  • Bones and joints

  • Cancer: Breast, ovarian

  • SLE

Valairat Dhamcharee, M.D.


Carrier testing

Carrier Testing

  • Thalassemia

  • Metabolic disorders

Valairat Dhamcharee, M.D.


Drug response

Drug Response

  • Alcohol Consumption

  • Smoking and health risk

  • Antidepressant Response

  • Beta-Blocker Response

  • Caffeine Metabolism

Valairat Dhamcharee, M.D.


What we are testing to determine a genetic risk

What we are testing to determine a genetic risk?

  • We are looking at “SNP” (Single Nucleotide Polymorphism) or “Genetic marker”.

Valairat Dhamcharee, M.D.


Genetics is who we are

Genetics is who we are

  • Most of your physical traits, such as eye color, hair color, and height, are inherited. So, too, are risks for health problems, such as heart disease, diabetes, and some cancers.

  • In fact, all diseases or medical conditions have a genetic component (except trauma).

Valairat Dhamcharee, M.D.


Gene panel training session

What are we made of?

Valairat Dhamcharee, M.D.


How important is dna

How important is DNA?

  • Your DNA affects every aspect of your health by helping to shape your risks for many different health conditions.

  • DNA is 99.9% identical among humans.

  • All our variations of shape, size and color are within that remaining 0.1% (DNA variants).

Valairat Dhamcharee, M.D.


Human dna

Human DNA

Valairat Dhamcharee, M.D.


Genetic dna variants

Genetic (DNA) Variants

  • Each of us is different because we carry a unique combination of genetic variants.

  • These DNA variants have been analyzed and found that some of these DNA variants affect our risk of developing diseases, such as cancer, heart attack and diabetes.

Valairat Dhamcharee, M.D.


Dna variants snps

DNA Variants = SNPs

  • A SNP, pronounced “snip”, is a single variation in the nucleotide sequence of DNA and stands for Single Nucleotide Polymorphism that can affect our inherited risk and a multitude of other characteristics.

Valairat Dhamcharee, M.D.


Dna variants snps1

DNA Variants (SNPs)

Valairat Dhamcharee, M.D.


Dna variants snps2

DNA Variants (SNPs)

Valairat Dhamcharee, M.D.


Genetic marker snp

Genetic Marker (SNP)

  • When a DNA variant is shown to be correlated with such a characteristic, this SNP can be referred to as a genetic marker for that disorder.

Valairat Dhamcharee, M.D.


Personalized genetic test

Personalized Genetic Test

  • Your genetic profile can indicate your potential genetic risk

  • It is in your genetic makeup that you can discover your predisposition for various conditions and diseases.

  • Once you are aware of those conditions, taking preventive measures is the next logical step.

Valairat Dhamcharee, M.D.


Goals of genetic markers analysis

Goals of Genetic Markers Analysis

  • Predictive

  • Preventive

  • Personalized

Valairat Dhamcharee, M.D.


How do we collect dna sample

How do we collect DNA sample?

Valairat Dhamcharee, M.D.


What happened to my dna

What happened to my DNA?

  • Labs will extract DNA from the cells found within saliva.

  • Analysis of DNA for SNPs.

  • The sample will be destroyed no more than 60 days after results are finalized.

  • DNA extract will be destroyed no more than one year from the most recently ordered report sample receipt date.

  • Request at any time that DNA be destroyed after testing

Valairat Dhamcharee, M.D.


Results

Results

  • Available in 4-6 weeks

Valairat Dhamcharee, M.D.


Genetic counseling is required before and after testings

Genetic counseling is required before and after testings

Valairat Dhamcharee, M.D.


What can you do if you have genetic risks

What can you do if you have genetic risks?

  • Supplements

  • Lifestyle change

Valairat Dhamcharee, M.D.


How do you know if i do the right thing

How do you know if I do the right thing?

  • Telomere test to measure telomere length

Valairat Dhamcharee, M.D.


How to prevent and follow the change results

How to prevent and follow the change results?

  • Genetic counseling for detail to prevent the disorders screened to be at risk

  • Follow the result by “Telomere test”

Valairat Dhamcharee, M.D.


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