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PALUMBO F.P. 1 – SERANTONI S. 2 – ABBRITTI F. 3 – MAZZOLA G. 4 - FAILLA G. 5 - DI SALVO M.M. 5

USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY. PALUMBO F.P. 1 – SERANTONI S. 2 – ABBRITTI F. 3 – MAZZOLA G. 4 - FAILLA G. 5 - DI SALVO M.M. 5. 1 – LABORATORIO DI VULNOLOGIA – PALERMO 2 – CASA DI CURA “VILLA FIORITA” – PRATO

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PALUMBO F.P. 1 – SERANTONI S. 2 – ABBRITTI F. 3 – MAZZOLA G. 4 - FAILLA G. 5 - DI SALVO M.M. 5

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  1. USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY PALUMBO F.P.1 – SERANTONI S.2 – ABBRITTI F.3 – MAZZOLA G.4- FAILLA G.5- DI SALVO M.M.5 1 – LABORATORIO DI VULNOLOGIA – PALERMO 2 – CASA DI CURA “VILLA FIORITA” – PRATO 3 – U.O. CHIRURGIA VASCOLARE – A.O. G. SALVINI, GARBAGNATE MILANESE 4 – U.O. MEDICINA TRASFUSIONALE – A.O.U. POLICLINICO, PALERMO 5 - U.O. ANGIOLOGIA – A.O.U. VITTORIO EMANUELE – “FERRAROTTO”, CATANIA

  2. USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY A new technological advanced device was tested on 27 lesions selected in 16 patients in a multicentric observational study. Age: 74 - 92 years Average age 81,6 yy AETIOLOGY Venous 5 Arterial 2 Mixed 3 Vasculitis 3 Diabetic 3 PALUMBO F.P. – SERANTONI S. – ABBRITTI F.– MAZZOLA G.- FAILLA G.- DI SALVO M.M.

  3. USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY METHODS Patients were selected according to conditions of the injury at time T0, regardless of time of onset and treatment prior to enrollment date. Criteria exclusion: severe infected lesions. All patients underwent to an anamnestic and clinical and instrumental evaluation (when required). Data were collected using a schedule to detect wound characteristics. QL index was administred to all patients. In selected patients, a multilayer, multicomponent, inelastic bandage was applied. Ulcer Cleansing System Device was administred before platelet gel application. Autologous PLT Gel was administred in 14 patients. Only in 2 patients homologous PLT Gel was administred. PALUMBO F.P. – SERANTONI S. – ABBRITTI F.– MAZZOLA G.- FAILLA G.- DI SALVO M.M.

  4. USE OF A NEW SURFACTANT GEL WITH SILVER SULPHADIAZINE IN THE TREATMENT OF CHRONIC LEG ULCERS AND DIABETIC FOOT: ITALIAN MULTICENTRIC EXPERIENCE USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY PALUMBO F.P. – SERANTONI S. – ABBRITTI F.– MAZZOLA G.- FAILLA G.- DI SALVO M.M.

  5. USE OF A NEW SURFACTANT GEL WITH SILVER SULPHADIAZINE IN THE TREATMENT OF CHRONIC LEG ULCERS AND DIABETC FOOT: ITALIAN MULTICENTRIC EXPERIENCE USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY RESULTS In all almost patients an improvement of obiective data was observed. Reduction of exudation and of inflamation in the skin around the ulcers were observed since the first week of gel application. These were accompanished by reduction of average wound areas and of pain. Also malodour decreased since the first week. Some patients have reported the occurrence of burning in the first two days of application of platelet gel. PALUMBO F.P. – SERANTONI S. – ABBRITTI F.– MAZZOLA G.- FAILLA G.- DI SALVO M.M.

  6. USE OF A NEW SURFACTANT GEL WITH SILVER SULPHADIAZINE IN THE TREATMENT OF CHRONIC LEG ULCERS AND DIABETIC FOOT: ITALIAN MULTICENTRIC EXPERIENCE USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY PAIN WOUND AREAS - 59,9 % - 31,1 % PALUMBO F.P. – SERANTONI S. – ABBRITTI F.– MAZZOLA G.- FAILLA G.- DI SALVO M.M.

  7. USE OF A NEW SURFACTANT GEL WITH SILVER SULPHADIAZINE IN THE TREATMENT OF CHRONIC LEG ULCERS AND DIABETIC FOOT: ITALIAN MULTICENTRIC EXPERIENCE USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY EXUDATE QL-INDEX -61,7% 10,2% PALUMBO F.P. – SERANTONI S. – ABBRITTI F.– MAZZOLA G.- FAILLA G.- DI SALVO M.M.

  8. USE OF A NEW SURFACTANT GEL WITH SILVER SULPHADIAZINE IN THE TREATMENT OF CHRONIC LEG ULCERS AND DIABETIC FOOT: ITALIAN MULTICENTRIC EXPERIENCE USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY Cleansing of a pressure ulcer in a patientaffected of PAD by device and application of PLT Gel. After 2 weeks growth of proliferative tissue. Cleansing of an ulceroccurring in a woman affected of thrombocytemia and application of PLT Gel. PALUMBO F.P. – SERANTONI S. – ABBRITTI F.– MAZZOLA G.- FAILLA G.- DI SALVO M.M.

  9. USEOF A NEW SURFACTANT GEL WITH SILVER SULPHADIAZINE IN THE TREATMENT OF CHRONIC LEG ULCERS AND DIABETIC FOOT: ITALIAN MULTICENTRIC EXPERIENCE USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY DISCUSSION The aim of the studywas to verify the effectiveness a new system of debridmentusing a solutionbased on poloxamer and moisturiserslike aloe vera. Cleansing and debridment, obtained with a tovelsoaked in thisliquid, wasfollowedimmediately by a feeling of freshnesseven on veryexuding and inflamedulcers. The application of platelet gel in some patientwasfollowed by the onset of burning of vatiableduration from a few hours up to twodays. Since the first twoapplicationsitwasobserved a decrease of exudate and dressingchanges to the reduction of inflamation of the tissuesurrounding the wound. Also the badodorwasreduceduntil the disappareance and thishasimproved the social life of the elderlysubjects. The handling and ease of use of the new debridmentsystemhasconsiderablyshortened time of PLT gel application. PALUMBO F.P. – SERANTONI S. – ABBRITTI F.– MAZZOLA G.- FAILLA G.- DI SALVO M.M.

  10. USE OF A NEW SURFACTANT GEL WITH SILVER SULPHADIAZINE IN THE TREATMENT OF CHRONIC LEG ULCERS AND DIABETIC FOOT: ITALIAN MULTICENTRIC EXPERIENCE USE OF A NEW ULCER CLEANSING SYSTEM AND OF PLATELET GEL IN THE MANAGEMENT OF “NON HEALING” LEG ULCERS IN ELDERLY • CONCLUSIONS • In almostallcasesweobserved an improvement in the wounds, indicated by: • Regression of signs of inflamation; • Reduction of exudate and fibrin; • Reduction of painassessed by the patients; • Goodcomplianceatdressingchange; • Reduction of malodour; • Improving QL-Index rate. • Theseresultsuggestthat a good bed woundpreparationisimportant to the next PLT gel action, • No collateraleffects and complicationswerereported in allpatients: AKNOWLEDGEMENTS A SPECIAL THANKS TO DR. ELSA LO IACONO AND DR. ELENA PATORNO FOR THE PREPARATION OF DATA ON PATIENTS. PALUMBO F.P. – SERANTONI S. – ABBRITTI F.– MAZZOLA G.- FAILLA G.- DI SALVO M.M.

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