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The Office for Research Facilitating Research – Driving Change

Nucleus of a cell from a patient suffering from Progeria. Courtesy of Robert Goldman, Feinberg School of Medicine. A mussel uses specialized proteins to adhere permanently onto wet surfaces. Courtesy of Phillip Messersmith, McCormick School of Engineering and Applied Sciences .

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The Office for Research Facilitating Research – Driving Change

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  1. Nucleus of a cell from a patient suffering from Progeria. Courtesy of Robert Goldman, Feinberg School of Medicine. A mussel uses specialized proteins to adhere permanently onto wet surfaces. Courtesy of Phillip Messersmith, McCormick School of Engineering and Applied Sciences The Office for ResearchFacilitating Research –Driving Change

  2. Outline • Trends: Global, National and Local • Areas to support • Faculty Research • Cores • Research Support • Centers • Northwestern’s Current Status - Metrics • Topics for Deeper Discussion … today’s agenda

  3. Office for Research: Our Basic Approach • Communicate with faculty, deans, national leaders • Identify trends and potential linkages • Respond: • Stimulate discussions • Match NU strengths to identified trends • Work with deans, chairs, center directors, faculty • Partner locally • Chicago Biomedical Consortium, Argonne, Fermi, Art Institute of Chicago, Field Museum, Shedd Aquarium, Chicago Botanic Garden, University of Chicago, University of Illinois (Chicago and Urbana) • Partner with companies, alumni, others • Develop functional and enduring structures that: • Result in societal impact • Train next generation of leaders (undergrads, grads, post docs, faculty)

  4. Office for Research: Agency for Change • General Approach • Strong leadership of the research agenda • Work closely with President, Provost, Deans, Center Directors and Faculty • Senior Leadership • Lewis Smith, MD – clinical and translational research, CTSA grant, IRBs, ACUC • Linda Hicke, PhD – life sciences research • Ann Adams, JD – research integrity • Don Workman, PhD – research operations • Meg McDonald, MBA – planning, finance, communications • Plan to recruit additional academic researchers in physical sciences and social sciences/humanities • Advisory committee • Senior faculty researchers to focus on big picture, strategic issues • Nimble, problem solvers • One Northwestern • Leadership role(s) • Close interaction with committee members • OR will “own” many of the issues that will be raised through this initiative

  5. Office for Research: Agency for Change • Local Partnerships: • Argonne, Fermi, and Chicago Biomedical Consortium are generally well established • Chicago Botanic Garden, Art Institute, Shedd Aquarium, and Field Museum can be strengthened • Opportunities with University of Chicago and University of Illinois need to be further explored • Strengthen Core Facilities • Computational Support for Research Data Needs • Proposal Development: • Assist faculty in making the proposals that support their work more competitive • Build a culture and provide training for faculty support • Compliance and Reporting • Increased complexity (i.e., Homeland Security) and growth leads to continued need to augment internal compliance oversight

  6. Office for Research: Stakeholders • The Schools • The Centers, Institutes, etc. • Deans, Faculty, post-docs, grad and undergrad students • Funding Agencies (federal, local, foundations, corporate, donors) • Government agencies • Not just the traditional ones of NIH, NSF, DOE, etc, but • Homeland Security • Federal Office for Research Integrity • Nuclear Regulatory Agency • DoT, FAA, EPA, CDC, DoJ, …

  7. Northwestern University Research • Strengths: • Interdisciplinary culture • Dedicated and responsive faculty • Increased financial support, esp. Lyrica funding • Challenges: • External grant funding flat or decreasing • Changing environment regarding commercialization of IP • Constraints: • Endowment and other funding • Space and facilities

  8. Office for Research: Major Challenges/Opportunities • Faculty hiring start-up and retention • Core and Shared facilities • Center for Comparative Medicine • Research computing • Cleanroom development • Research support unit staffing • Associate vice presidents for research and advisory committee • Center space

  9. Global Trends The Richard Smalley Top 10 List Problems • 1. Energy • 2. Water • 3. Food • 4. Environment • 5. Poverty • 6. Terrorism and war • 7. Disease • 8. Education • 9. Democracy • 10. Population Sustainability Public Policy and Economics Health Care (and Economics) Governance and Development

  10. Health Care Research Cancer Cardiovascular Disease Diabetes Neurodegenerative Genomics Proteomics Bacterial/ Viral/ Parasitic Obesity Health Care Economics (Curative Preventative) Translational Basic/Applied Science Energy Nanotechnology Materials Cell/ Molecular Biology Neurology Cognitive Sciences Social Sciences Governance Development Religion Ethics National Trends – An Evolving List We must match Northwestern Strengths with global and national trends.

  11. The External Research Environment • NIH Institute budgets for FY2008 are set at the same amounts as FY2007; one exception is a small increase for the Global Fund for HIV/AIDS. • NSF will receive a small increase of 2.0% from FY2007, which includes an increase of 3.3% for the Education and Human Resources budget. • DOE’s Science division will receive a 4.6% increase overall. The funding for Energy R&D will increase by 23% to $1.9 billion. The International Linear Collider was funded at $15 million of the $60 million requested.

  12. The External Research Environment - Conclusions • Northwestern must find ways to make our investigators’ proposals more competitive: • Better support and streamlined processes for clinical trials • Minimization of barriers to collaboration • Inter-departmental and inter-campus, cross school and departments • Center vs. department/school conflicts • External partners • Industry, particularly in intellectual property and clinical trials support • Support and mentoring for junior investigators • Continuously improving administrative and programmatic support • “One Northwestern” means that the sum = more than the parts

  13. Programmatic Support: Core Facilities • Continues to be raised as a “greatest need” item by faculty and deans • Instrumentation funding, including matching when grant funding is available • Operational support: personnel and maintenance • Core Facilities Committee is being charged with developing a coherent, institutional management strategy and priorities; initial report presented in Fall 2007 • One Northwestern Financial Systems and Modeling Task Force is addressing this issue as well; report submitted April 2008 • Already-identified big-ticket facilities • Proteomics • Cleanrooms • BioInformatics • Animals

  14. Northwestern University Awards

  15. Northwestern University Proposals

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