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Epidemiology and Prevention of Viral Hepatitis A to E:. Hepatitis Branch Centers for Disease Control and Prevention. An Overview. Viral Hepatitis - Historical Perspective. Enterically transmitted. “Infectious”. A. E. Viral hepatitis. NANB. Parenterally transmitted. B. D. C.

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Epidemiology and prevention of viral hepatitis a to e
Epidemiology and Prevention of Viral Hepatitis A to E:

Hepatitis Branch

Centers for Disease Control and Prevention

An Overview


Viral Hepatitis - Historical Perspective

Enterically

transmitted

“Infectious”

A

E

Viral hepatitis

NANB

Parenterally

transmitted

B

D

C

“Serum”

F, G,

? other


Viral Hepatitis - Overview

Type of Hepatitis

A

B

C

D

E

Source of

feces

blood/

blood/

blood/

feces

virus

blood-derived

blood-derived

blood-derived

body fluids

body fluids

body fluids

Route of

fecal-oral

percutaneous

percutaneous

percutaneous

fecal-oral

transmission

permucosal

permucosal

permucosal

Chronic

no

yes

yes

yes

no

infection

Prevention

pre/post-

pre/post-

blood donor

pre/post-

ensure safe

exposure

exposure

screening;

exposure

drinking

immunization

immunization

risk behavior

immunization;

water

modification

risk behavior

modification


Acute Viral Hepatitis by Type, United States, 1982-1993

34%

47%

16%

Hepatitis A

Hepatitis B

Hepatitis C

3%

Hepatitis

Non-ABC

Source: CDC Sentinel Counties Study on Viral Hepatitis


Estimates of acute and chronic disease burden for viral hepatitis united states
Estimates of Acute and Chronic DiseaseBurden for Viral Hepatitis, United States

HAV

HBV

HCV

HDV

Acute infections

(x 1000)/year*

125-200

140-320

35-180

6-13

Fulminant

deaths/year

100

150

?

35

Chronic

0

1-1.25

3.5

infections

million

million

70,000

Chronic liver disease

deaths/year

0

5,000

8-10,000

1,000

* Range based on estimated annual incidence, 1984-1994.


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