What is so memorable about CREBBP?. (RSTS; RTS, CBP CBP/MOZ FUSION GENE, CREB-binding protein). Where is it found?. What exactly does “BP” mean. Binding protien What is a coactivator and what is its role? Does it perform one function (interaction) or does it perform many? pg224 of book
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(RSTS; RTS, CBP CBP/MOZ FUSION GENE, CREB-binding protein)
It is made of 32 exons and 31 introns. The mRNA itself is 8.7 kb, 7.3 of that is coding!
Zinc finger ZZ type
TAZ zinc finger
Two Domains of unknown functions (interact with other pfams
Ridley, Matt. "Chromosome 16, Memory." Genome, The Autobiography of a species in23 Chapters. New York: Harper Perennial, 1999. 219-230.
http://www.dsi.univ-paris5.fr/genatlas/fiche.php?symbol=CREBBP (slide 2,6)
http://atlasgeneticsoncology.org/Genes/CBPID42.html (slide 10)
http://genome-www5.stanford.edu/cgi-bin/source/sourceResult?criteria=CREBBP&choice=Gene&option=Symbol&organism=Hs (slide 4, 8)
http://www.ihop-net.org/UniPub/iHOP/gismo/87420.html (slide and 9)
http://www.ncbi.nlm.nih.gov/genome/guide/human/ (slide 1)
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=full_report&list_uids=1387 (slide 5)
http://www.ebi.ac.uk/intact/search/do/search?searchString=EBI-81215&filter=ac&searchClass=Protein&view=partner&filter=ac (slide 3)
http://www.sanger.ac.uk/cgi-bin/Pfam/qquerypfam.pl?terms=crebbp (slide 7)