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Substance-Use Disorders. Substance Abuse DSM-IV-TR CriteriaRecurrent substance-related legal problemsContinued substance use despite having persistent or recurrent social or interpersonal problems. . Substance DependencePhysical dependenceSubstance Dependence (cont.)Psychological dependenceExtremely powerful, producing intense craving for a substance as well as compulsive use of itSubstance Dependence DSM-IV-TR Criteria Evidence of toleranceEvidence of withdrawalSymptoms associated w9457

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