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ALSPAC Data. Measures of Childhood Incontinence. Or, if you’re squeamish…. How many kittens do you own?. Repeated questions:. Repeated questions: - Binary. Zero. One. Repeated questions: - Ordinal. Zero. One. Two ~ DSM4 criterion. Repeated questions. Asked at: 4½ years ~ KK

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ALSPAC Data

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ALSPAC Data

Measures of Childhood Incontinence


Or, if you’re squeamish…


How many kittens do you own?


Repeated questions:


Repeated questions: - Binary

Zero

One


Repeated questions: - Ordinal

Zero

One

Two ~ DSM4 criterion


Repeated questions

  • Asked at:

  • 4½ years ~ KK

  • 5½ years ~ KM

  • 6½ years ~ KP

  • 7½ years ~ KR

  • 9½ years ~ KU


Why mixture models?

  • Previous work (clinical/epidemiological) has provided evidence for subgroups

    • Different aetilogies

    • Different comorbid factors

    • Different long-term outcomes

  • Variability in development poorly captured by standard growth models

    • Relapsing group


BW frequencies (complete case)


Infrequent bedwetting


Frequent Bedwetting


Planned models

  • LLCA replication of Croudace AJE model

    • Incorporate covariates into above

  • LLCA/LCGA models of frequent wetters (binary)

    • Assessment of gender invariance with knownclass

  • Parallel modelling of day/night wetting

  • Ordinal modelling of 3-level measures

    • Incorporate covariates

    • Risk of later binary outcome


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