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ALSPAC Data. Measures of Childhood Incontinence. Or, if you’re squeamish…. How many kittens do you own?. Repeated questions:. Repeated questions: - Binary. Zero. One. Repeated questions: - Ordinal. Zero. One. Two ~ DSM4 criterion. Repeated questions. Asked at: 4½ years ~ KK

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ALSPAC Data

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Alspac data

ALSPAC Data

Measures of Childhood Incontinence


Or if you re squeamish

Or, if you’re squeamish…


How many kittens do you own

How many kittens do you own?


Repeated questions

Repeated questions:


Repeated questions binary

Repeated questions: - Binary

Zero

One


Repeated questions ordinal

Repeated questions: - Ordinal

Zero

One

Two ~ DSM4 criterion


Repeated questions1

Repeated questions

  • Asked at:

  • 4½ years ~ KK

  • 5½ years ~ KM

  • 6½ years ~ KP

  • 7½ years ~ KR

  • 9½ years ~ KU


Why mixture models

Why mixture models?

  • Previous work (clinical/epidemiological) has provided evidence for subgroups

    • Different aetilogies

    • Different comorbid factors

    • Different long-term outcomes

  • Variability in development poorly captured by standard growth models

    • Relapsing group


Bw frequencies complete case

BW frequencies (complete case)


Infrequent bedwetting

Infrequent bedwetting


Frequent bedwetting

Frequent Bedwetting


Planned models

Planned models

  • LLCA replication of Croudace AJE model

    • Incorporate covariates into above

  • LLCA/LCGA models of frequent wetters (binary)

    • Assessment of gender invariance with knownclass

  • Parallel modelling of day/night wetting

  • Ordinal modelling of 3-level measures

    • Incorporate covariates

    • Risk of later binary outcome


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