PERFUSION MRI IMAGING. Dr. Mohamed El Safwany , MD. Intended learning outcome. The student should learn at the end of this lecture principles of Perfusion MRI studies. Perfusion imaging. Definitions Principles Some more definitions Perfusion technique Applications Future. Definitions.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Dr. Mohamed El Safwany, MD.
The student should learn at the end of this lecture principles of Perfusion MRI studies.
After injection of a contrast agent
At each voxel we observe : relaxation rates concentration of local contrast.
~ ‘mean transit time’
cerebral blood volume
Hemodynamics Bl. volume relaxation rates concentration of local contrast.
Aim 1. Diagnosis
2. Monitoring management
3. Understanding intracranial lesions
Dynamic MR perfusion
rCBV relaxation rates concentration of local contrast.
rCBV, processed with “Negative Enhancement Integral”(NEI)
is related to area under curve
MTT relaxation rates concentration of local contrast.
MTT is related to the time to peak and to the width of the peak ; it is processed with “Mean Time to Enhance“(MTE)
Requires very high
power injector - Gadolium
1 - Start Imaging
2 - Inject Contrast*
3 - Continue Imaging
10 slices - 50 images of each slice - TOTAL time 1:34 min
*Push Gadolinium with 20 cc of saline flush
Stroke relaxation rates concentration of local contrast.Perfusion Imaging: Findings in Infarction
David Sutton’s Radiology
Clark’s Radiographic positioning and techniques
Two students will be selected for assignment.
Describe the rCBF, rCBV & MTT?