PERFUSION MRI IMAGING. Dr. Mohamed El Safwany , MD. Intended learning outcome. The student should learn at the end of this lecture principles of Perfusion MRI studies. Perfusion imaging. Definitions Principles Some more definitions Perfusion technique Applications Future. Definitions.
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Dr. Mohamed El Safwany, MD.
The student should learn at the end of this lecture principles of Perfusion MRI studies.
After injection of a contrast agent
Passage of Gd. can be followed by the changes in the relaxation rates concentration of local contrast.
~ ‘mean transit time’
cerebral blood volume
Aim 1. Diagnosis
2. Monitoring management
3. Understanding intracranial lesions
Dynamic MR perfusion
rCBV, processed with “Negative Enhancement Integral”(NEI)
is related to area under curve
MTT is related to the time to peak and to the width of the peak ; it is processed with “Mean Time to Enhance“(MTE)
Requires very high
power injector - Gadolium
1 - Start Imaging
2 - Inject Contrast*
3 - Continue Imaging
10 slices - 50 images of each slice - TOTAL time 1:34 min
*Push Gadolinium with 20 cc of saline flush
David Sutton’s Radiology
Clark’s Radiographic positioning and techniques
Two students will be selected for assignment.
Describe the rCBF, rCBV & MTT?